Lung cancer continues to be the leading cause of cancer-related death worldwide. In the last
decade, significant advancements in the diagnosis and treatment of lung cancer, particularly …

Diabetic ulcers (DUs) are one of the most serious complications of diabetes mellitus. The
application of a functional dressing is a crucial step in DU treatment and is associated with …

Neoadjuvant immunotherapy has emerged as a promising approach in the treatment of
various malignancies, with preclinical studies showing improved immune responses in the …

Background Lactate accumulation leads to an acidic tumor microenvironment (TME), in turn
promoting colorectal cancer (CRC) progression. Tumor-associated macrophages (TAMs) …

Lung cancer accounts for a relatively high proportion of malignant tumors. As the most
prevalent type of lung cancer, non-small cell lung cancer (NSCLC) is characterized by high …

Immune checkpoint inhibitors (ICIs) in the form of anti-CTLA-4 and anti-PD-1/PD-L1 have
become the frontier of cancer treatment and successfully prolonged the survival of patients …

Immunotherapy has changed the treatment strategy of non-small cell lung cancer (NSCLC)
in recent years, among which anti-PD-1/PD-L1 antibodies are the most used. However, the …

Immune checkpoint blockade (ICB) therapy works by inhibiting suppressive checkpoints that
become upregulated after T cell activation, like PD-1/PD-L1 and CTLA-4. While the initial …

The treatment of non-small cell lung cancer (NSCLC) has increasingly been driven by the
presence of targetable driver mutations, including epidermal growth factor receptor (EGFR) …

The advent of immunotherapy, especially immune checkpoint inhibitors (ICIs), has
revolutionized antitumor therapy. Programmed cell death receptor 1 (PD-1) and …