Accumulation of senescent cells affects organismal aging and the prevalence of age-
associated disease. Emerging evidence suggests that activation of autophagy protects …

Mammalian preimplantation embryogenesis depends on the spatio-temporal dynamics of
the microtubule cytoskeleton to enable exceptionally fast changes in cell number, function …

Teleost eggs have evolved a highly derived early developmental pattern within vertebrates
as a result of the meroblastic cleavage pattern, giving rise to a polar stratified architecture …

Background Osteoarthritis (OA) is a common degenerative joint disease and causes chronic
pain and disability to the elderly. Several risk factors are involved, such as aging, obesity …

Metastasis is responsible for approximately 90% of cancer-associated mortality and
proceeds through multiple steps. Several herbal medicines are reported to inhibit primary …

Caffeine exerts a biphasic effect on zebrafish behavior. High doses of caffeine have been
associated with increased stress and anxiety, whereas low doses have been found to …

The enzyme acyl-CoA: cholesterol acyltransferase (ACAT) is normally localized in the
endoplasmic reticulum (ER) where it can esterify cholesterol for storage in lipid droplets …

The freeze-tolerant wood frogs, Rana sylvatica are one of only a few vertebrate species in
the animal kingdom, which are extensively studied to understand vertebrate freeze …

Metastasis, a leading contributor to the morbidity of cancer patients, occurs through multiple
steps. As each of these steps is promoted by different molecular mechanisms, blocking …

The present thesis encompasses a work on the effect of Gold Nanoparticles on the growth,
development and behaviour of Zebrafish. In the present times, when science and technology …