Renal branching morphogenesis: concepts, questions, and recent advances

F Costantini - Differentiation, 2006 - Wiley Online Library
The ureteric bud (UB) is an outgrowth of the Wolffian duct, which undergoes a complex
process of growth, branching, and remodeling, to eventually give rise to the entire urinary …

Cellular and molecular mechanisms of kidney development: from the embryo to the kidney organoid

N Khoshdel Rad, N Aghdami… - Frontiers in cell and …, 2020 - frontiersin.org
Development of the metanephric kidney is strongly dependent on complex signaling
pathways and cell–cell communication between at least four major progenitor cell …

Prevalence of mutations in renal developmental genes in children with renal hypodysplasia: results of the ESCAPE study

S Weber, V Moriniere, T Knüppel… - Journal of the …, 2006 - journals.lww.com
Renal hypodysplasia (RHD) is characterized by a reduced nephron number, small kidney
size, and disorganized renal tissue. A hereditary basis has been established for a subset of …

Vesicoureteral reflux

G Williams, JT Fletcher, SI Alexander… - Journal of the American …, 2008 - journals.lww.com
Vesicoureteral reflux (VUR), the retrograde flow of urine from the bladder toward the kidney,
is common in young children. About 30% of children with urinary tract infections will be …

SIX2 and BMP4 mutations associate with anomalous kidney development

S Weber, JC Taylor, P Winyard, KF Baker… - Journal of the …, 2008 - journals.lww.com
Renal hypodysplasia (RHD) is characterized by reduced kidney size and/or
maldevelopment of the renal tissue following abnormal organogenesis. Mutations in renal …

A gene implicated in activation of retinoic acid receptor targets is a novel renal agenesis gene in humans

PD Brophy, M Rasmussen, M Parida, G Bonde… - Genetics, 2017 - academic.oup.com
Renal agenesis is a devastating birth defect, and although genes encoding retinoic acid
signaling components have been shown to be important for renal... Renal agenesis (RA) is …

[HTML][HTML] Canonical WNT/β-catenin signaling is required for ureteric branching

D Bridgewater, B Cox, J Cain, A Lau, V Athaide… - Developmental …, 2008 - Elsevier
WNT/β-catenin signaling has an established role in nephron formation during kidney
development. Yet, the role of β-catenin during ureteric morphogenesis in vivo is undefined …

USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney

M Yanagita, M Oka, T Watabe, H Iguchi, A Niida… - Biochemical and …, 2004 - Elsevier
Bone morphogenetic proteins (BMPs) play critical roles in cellular proliferation,
differentiation, and programmed cell death in multiple tissues. An increasing body of recent …

[HTML][HTML] Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1

MA Basson, J Watson-Johnson, R Shakya… - Developmental …, 2006 - Elsevier
Branching of ureteric bud-derived epithelial tubes is a key morphogenetic process that
shapes development of the kidney. Glial cell line-derived neurotrophic factor (GDNF) …

Novel genetic aspects of congenital anomalies of kidney and urinary tract

S Weber - Current opinion in pediatrics, 2012 - journals.lww.com
Novel genetic aspects of congenital anomalies of kidney and... : Current Opinion in Pediatrics
Novel genetic aspects of congenital anomalies of kidney and urinary tract : Current Opinion in …