S Mohana Roopan, R Sompalle - Synthetic Communications, 2016 - Taylor & Francis
This review is an attempt to compile the literature of various synthetic procedures of pyrimidine analogs. Pyrimidine and its fused pyrimidine derivatives are a class of …
On the account of the reported anticancer activity of pyrazolo [3, 4-d] pyrimidines, a new series of pyrazolo [3, 4-d] pyrimidine derivatives were synthesized and tested for in-vitro …
RA Mekheimer, SMR Allam, MA Al-Sheikh… - Bioorganic …, 2022 - Elsevier
A novel series of pyrimido [5, 4-c] quinoline derivatives variously substituted at positions 2 and 5 have been synthesized, in good to excellent yields, via rapid base-catalyzed …
D Kumar, S Kumar Jain - Current Medicinal Chemistry, 2016 - ingentaconnect.com
Scientific community is striving to understand the role of heterocycles and fused heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …
Some novel quinolines and pyrimido [4, 5-b] quinolines have been synthesized. The structures of which were confirmed by elemental analyses and spectral data. All the target …
PS Sharma, R Sharma, T Tyagi - Current cancer drug targets, 2011 - ingentaconnect.com
Angiogenesis, the formation of new blood vessels from pre-existing ones, plays a central role in the process of tumor growth and metastasis. The proliferation of endothelium and …
MM Ghorab, FA Ragab, HI Heiba, HA Youssef… - Bioorganic & medicinal …, 2010 - Elsevier
Pyrroles and pyrrolo [2, 3-d] pyrimidines were reported to act as potent anticancer agents, in this work, a series of novel 2-substituted-3-cyano-4-phenyl-pyrrole 5, 6, 11–18, and 5-phenyl …
In our continuing efforts to develop therapeutically active coumarin‐based compounds, a series of new C4–C4′ biscoumarin–pyrimidine conjugates (1a–l) was synthesized via SN2 …
SA Al-Issa - Saudi Pharmaceutical Journal, 2013 - Elsevier
On account of the reported anticancer of pyrimidine and condensed pyrimidine, a new pyrimido [3, 2-b]-1, 2, 4, 5-tetrazine 3a, b, 5c, d, 6, 9, pyrimido [3, 2-b]-1, 2, 4-triazine 10, 11 …