Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth

SI Hamdallah, R Zoqlam, P Erfle, M Blyth… - International journal of …, 2020 - Elsevier
Using micro-sized channels to manipulate fluids is the essence of microfluidics which has
wide applications from analytical chemistry to material science and cell biology research …

A comprehensive review of one decade of microfluidic platforms applications in synthesis of enhanced carriers utilized in controlled drug delivery

S Siavashy, M Soltani, M Ahmadi… - Advanced Materials …, 2022 - Wiley Online Library
Novel nanocarriers such as multifunctional nanoparticles (NPs) have recently attracted
attention due to their various applications, specifically in medicine and treatment. However, it …

Microfluidics in drug delivery: review of methods and applications

M Rawas-Qalaji, R Cagliani, N Al-Hashimi… - Pharmaceutical …, 2023 - Taylor & Francis
Microfluidics technology has emerged as a promising methodology for the fabrication of a
wide variety of advanced drug delivery systems. Owing to its ability for accurate handling …

Design and Bottom-up Production of an Aerosolizable Cannabidiol Nanosuspension

L Casula, M Schlich, MC Cardia, E Lai… - Molecular …, 2024 - ACS Publications
Cannabidiol (CBD), a small nonpsychoactive molecule derived from Cannabis sativa, exerts
a variety of therapeutic actions, such as anti-inflammatory, antioxidant, and antibacterial …

Factors to consider when selecting a nebulizer for a new inhaled drug product development program

M Elphick, D von Hollen, JN Pritchard… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Nebulizers are a common device choice for use when developing a new drug
product, but the range of nebulizer devices available can make it difficult to select the right …

Novel budesonide particles for dry powder inhalation prepared using a microfluidic reactor coupled with ultrasonic spray freeze drying

D Saboti, U Maver, HK Chan, O Planinšek - Journal of Pharmaceutical …, 2017 - Elsevier
Budesonide (BDS) is a potent active pharmaceutical ingredient, often administered using
respiratory devices such as metered dose inhalers, nebulizers, and dry powder inhalers …

The Development of Novel Ganoderic-Acid-Encapsulated Nanodispersions Using the Combination of Ultrasonic Cavitation and Solvent Evaporation through …

WK Cheng, KW Tan, SY Tang, PG Cheng, CH Pang… - Sustainability, 2023 - mdpi.com
Ganoderic Acid (GA), a major bioactive compound isolated from the East Asian medicinal
mushroom Ganoderma tsugae, is traditionally believed to have significant medicinal …

[PDF][PDF] Genotoxicity of noscapine nanosuspension prepared by microfluidic reactors on HepG2 cell line

M Azarian, A Amani, MA Faramarzi, A Eidi… - Iranian Journal of …, 2020 - ijcce.ac.ir
Noscapine is an antispasmodic alkaloid used as antitussive and anti-cough obtained from
plants about Papaveraceae family which this benzylisoquinoline alkaloid and its synthetic …

Production, characterisation, and in vitro nebulisation performance of budesonide-loaded PLA nanoparticles

MA Amini, MA Faramarzi, K Gilani… - Journal of …, 2014 - Taylor & Francis
The aim of this study is to prepare a nanosuspension of budesonide for respiratory delivery
using nebuliser by optimising its particle size and characterising its in vitro deposition …

Saponin micelles lead to high mucosal permeation and in vivo efficacy of solubilized budesonide

S Nakowitsch, C Koller, JM Seifert, M König-Schuster… - Pharmaceutics, 2020 - mdpi.com
Due to fast nasal mucociliary clearance, only the dissolved drug content can effectively
permeate the mucosa and be pharmaceutically active after intranasal application of …