Despite decades of bile acid research, diverse biological roles for bile acids have been
discovered recently due to developments in understanding the human microbiota. As …

The diversity, composition, and function of the bacterial community inhabiting the human
gastrointestinal tract contributes to host health through its role in producing energy or …

The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

Bile acids (BAs) mediate the crosstalk between human and microbial cells and influence
diseases including Clostridioides difficile infection (CDI). While bile salt hydrolases (BSHs) …

Determining the structure and phenotypic context of molecules detected in untargeted
metabolomics experiments remains challenging. Here we present reverse metabolomics as …

Most processing of the human diet occurs in the small intestine. Metabolites in the small
intestine originate from host secretions, plus the ingested exposome and microbial …

Bacteria in the gastrointestinal tract produce amino acid bile acid amidates that can affect
host-mediated metabolic processes,,,,–; however, the bacterial gene (s) responsible for their …

Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-
soluble vitamins while shaping the gut microbiome because of their antimicrobial …

Polysaccharides are known to confer protection against obesity via modulation of gut
microbiota. To expand our knowledge of mushroom-derived prebiotics, we investigated the …

Bile acids (BAs) as cholesterol-derived molecules play an essential role in some
physiological processes such as nutrient absorption, glucose homeostasis and regulation of …