Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite

I Mueller, MR Galinski, JK Baird, JM Carlton… - The Lancet infectious …, 2009 - thelancet.com
Plasmodium vivax is geographically the most widely distributed cause of malaria in people,
with up to 2· 5 billion people at risk and an estimated 80 million to 300 million clinical cases …

Designing the next generation of medicines for malaria control and eradication

JN Burrows, R Hooft van Huijsduijnen, JJ Möhrle… - Malaria journal, 2013 - Springer
In the fight against malaria new medicines are an essential weapon. For the parts of the
world where the current gold standard artemisinin combination therapies are active …

Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data

T Carver, SR Harris, M Berriman, J Parkhill… - …, 2012 - academic.oup.com
Motivation: High-throughput sequencing (HTS) technologies have made low-cost
sequencing of large numbers of samples commonplace. An explosion in the type, not just …

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

JM Carlton, JH Adams, JC Silva, SL Bidwell, H Lorenzi… - Nature, 2008 - nature.com
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

TD Otto, U Böhme, AP Jackson, M Hunt… - BMC biology, 2014 - Springer
Background Rodent malaria parasites (RMP) are used extensively as models of human
malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA …

Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutations

T Rouxel, J Grandaubert, JK Hane, C Hoede… - Nature …, 2011 - nature.com
Fungi are of primary ecological, biotechnological and economic importance. Many
fundamental biological processes that are shared by animals and fungi are studied in fungi …

Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution

X Su, KD Lane, L Xia, JM Sá… - Clinical microbiology …, 2019 - Am Soc Microbiol
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

New insights into the blood‐stage transcriptome of Plasmodium falciparum using RNA‐Seq

TD Otto, D Wilinski, S Assefa, TM Keane… - Molecular …, 2010 - Wiley Online Library
Recent advances in high‐throughput sequencing present a new opportunity to deeply probe
an organism's transcriptome. In this study, we used Illumina‐based massively parallel …

Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes

RW Moon, J Hall, F Rangkuti, YS Ho… - Proceedings of the …, 2013 - National Acad Sciences
Research into the aetiological agent of the most widespread form of severe malaria,
Plasmodium falciparum, has benefitted enormously from the ability to culture and genetically …

Plasmodium knowlesi: Reservoir Hosts and Tracking the Emergence in Humans and Macaques

KS Lee, PCS Divis, SK Zakaria, A Matusop… - PLoS …, 2011 - journals.plos.org
Plasmodium knowlesi, a malaria parasite originally thought to be restricted to macaques in
Southeast Asia, has recently been recognized as a significant cause of human malaria …