The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

The NLRP3 inflammasome is a multimeric cytosolic protein complex that assembles in
response to cellular perturbations. This assembly leads to the activation of caspase-1, which …

Obesity is a state of low-grade chronic inflammation that causes multiple metabolic
diseases. During obesity, signalling via cytokines of the TNF family mediate cell death and …

Although obesity is typically associated with metabolic dysfunction and cardiometabolic
diseases, some people with obesity are protected from many of the adverse metabolic …

Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …

The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …

Obesity is a serious medical condition worldwide, which needs new approaches and
recognized international consensus in treating diseases leading to morbidity. The aim of this …

Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …

Chronic low-grade inflammation is a recognized key feature associated with type 2 diabetes
mellitus (T2DM) and its complications. In prospective randomized trials, sodium-glucose …