Effects of ionizing radiation on the heart

M Boerma, V Sridharan, XW Mao, GA Nelson… - … Research/Reviews in …, 2016 - Elsevier
This article provides an overview of studies addressing effects of ionizing radiation on the
heart. Clinical studies have identified early and late manifestations of radiation-induced …

The role of mitochondrial dysfunction in radiation-induced heart disease: from bench to bedside

K Livingston, RA Schlaak, LL Puckett… - Frontiers in …, 2020 - frontiersin.org
Radiation is a key modality in the treatment of many cancers; however, it can also affect
normal tissues adjacent to the tumor, leading to toxic effects. Radiation to the thoracic …

Redox interactions-induced cardiac toxicity in cancer therapy

X Fu, J Tang, P Wen, Z Huang, M Najafi - Archives of biochemistry and …, 2021 - Elsevier
Cancer patients undergoing radiotherapy, chemotherapy, or targeted cancer therapy are
exposed to the risk of several side effects because of the heavy production of ROS by …

Radiation-induced alterations in mitochondria of the rat heart

V Sridharan, N Aykin-Burns, P Tripathi… - Radiation …, 2014 - meridian.allenpress.com
Radiation therapy for the treatment of thoracic cancers may be associated with radiation-
induced heart disease (RIHD), especially in long-term cancer survivors. Mechanisms by …

Apoptosis induction of cardiomyocytes and subsequent fibrosis after irradiation and neoadjuvant chemotherapy

C Salata, SC Ferreira-Machado… - … journal of radiation …, 2014 - Taylor & Francis
Purpose: Breast cancer treatments can induce important cardiovascular complications. The
aim of this study was to evaluate cardiac alterations after irradiation and chemotherapy in an …

Preliminary pre-clinical studies on the side effects of breast cancer treatment

C Salata, CE deAlmeida… - … journal of radiation …, 2021 - Taylor & Francis
Purpose: Technological advancement in the treatment of cancer together with early
detection and diagnosis have considerably improved the survival of breast cancer patients …

Radiotherapy-induced heart disease: a review of the literature

B Zou, JP Schuster, K Niu, Q Huang… - Precision Clinical …, 2019 - academic.oup.com
Radiotherapy as one of the four pillars of cancer therapy plays a critical role in the
multimodal treatment of thoracic cancers. Due to significant improvements in overall cancer …

A novel approach of using Maca root as a radioprotector in a rat testicular damage model focusing on GRP78/CHOP/Caspase-3 pathway

MH Mekkawy, FY Abdou, MM Ali… - Archives of Biochemistry …, 2024 - Elsevier
Purpose Despite the effectiveness of ionizing radiation in treating cancer, it can damage
healthy tissues in the vicinity. Due to the high radio-sensitivity of testicular tissues, radiation …

Microbeam irradiation of the beating rodent heart: An ex vivo study of acute and subacute effects on cardiac function

F Lange, T Kirschstein, J Davis, J Paino… - International Journal of …, 2022 - Elsevier
Purpose Microbeam radiation therapy (MRT) has shown several advantages compared with
conventional broad-beam radiation therapy in small animal models, including a better …

[HTML][HTML] Alterations in low-z elements distribution in heart tissue after treatments to breast cancer using LEXRF technique

A Mantuano, RC Barroso, LP Nogueira… - American Journal of …, 2016 - scirp.org
Data from Global Cancer Statistics show that breast cancer (BC) is the most common type of
cancer among women, leading the number of deaths caused by cancer. The developments …