Bacterial meningitis is an inflammation of the meninges which covers and protects the brain
and the spinal cord. Such inflammation is mostly caused by blood-borne bacteria that cross …

Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region,
country, pathogen, and age group; being a life-threatening disease with a high case fatality …

Infections caused by Streptococcus pneumoniae (also known as pneumococci) pose a
threat to human health. Pneumococcal infections are the most common cause of milder …

Pneumococcal meningitis, inflammation of the meninges due to an infection of the Central
Nervous System caused by Streptococcus pneumoniae (the pneumococcus), is the most …

Pneumolysin (PLY) is a pore-forming toxin produced by the human pathobiont
Streptococcus pneumoniae, the major cause of pneumonia worldwide. PLY, a key …

Bacterial meningitis is a serious central nervous system (CNS) infection, claiming millions of
human lives annually around the globe. The deadly infection involves severe inflammation …

Streptococcus pneumoniae, a common cause of community-acquired bacterial pneumonia,
can cross the respiratory epithelial barrier to cause lethal septicemia and meningitis. S …

Bacterial meningitis is a catastrophic nervous system disorder with high mortality and wide
range of morbidities. Some of the meningitis-causing bacteria occupy cholesterol dependent …

Abstract Treatment of pneumococcal infections is limited by antibiotic resistance and
exacerbation of disease by bacterial lysis releasing pneumolysin toxin and other …

Pathogenic mycobacteria gain entry to their hosts by inhalation or ingestion where they
adhere to different cell types and are subsequently internalized by professional phagocytic …