Targeting cancer stem cells for reversing therapy resistance: mechanism, signaling, and prospective agents
HM Zhou, JG Zhang, X Zhang, Q Li - Signal transduction and targeted …, 2021 - nature.com
Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …
contribute to tumor progression and therapy resistance. However, the underlying processes …
ATP‐binding cassette (ABC) transporters in cancer: A review of recent updates
The ATP‐binding cassette (ABC) transporter superfamily is one of the largest membrane
protein families existing in wide spectrum of organisms from prokaryotes to human. ABC …
protein families existing in wide spectrum of organisms from prokaryotes to human. ABC …
[HTML][HTML] ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance
W Muriithi, LW Macharia, CP Heming… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
The ATP-binding cassette transporters (ABC transporters) have been intensely studied over
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype …
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype …
Epigenetic modifications and head and neck cancer: implications for tumor progression and resistance to therapy
Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …
The role of ABC transporters in ovarian cancer progression and chemoresistance
Over 80% of ovarian cancer patients develop chemoresistance which results in a lethal
course of the disease. A well-established cause of chemoresistance involves the family of …
course of the disease. A well-established cause of chemoresistance involves the family of …
Clinical implications of colorectal cancer stem cells in the age of single-cell omics and targeted therapies
The cancer stem cell (CSC) concept emerged from the recognition of inherent tumor
heterogeneity and suggests that within a given tumor, in analogy to normal tissues, there …
heterogeneity and suggests that within a given tumor, in analogy to normal tissues, there …
Autophagy regulates cisplatin‐induced stemness and chemoresistance via the upregulation of CD 44, ABCB 1 and ADAM 17 in oral squamous cell carcinoma
Objective We inspected the relevance of CD 44, ABCB 1 and ADAM 17 in OSCC stemness
and deciphered the role of autophagy/mitophagy in regulating stemness and …
and deciphered the role of autophagy/mitophagy in regulating stemness and …
Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades
T Efferth, O Kadioglu, MEM Saeed, EJ Seo… - Phytochemistry …, 2021 - Springer
Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …
Cancer stem cell markers in head and neck squamous cell carcinoma
AG Major, LP Pitty, CS Farah - Stem cells international, 2013 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is one of the world's top ten most
common cancers. Current survival rates are poor with only 50% of patients expected to …
common cancers. Current survival rates are poor with only 50% of patients expected to …
Biomarkers in diagnosis and therapy of oral squamous cell carcinoma: A review of the literature
S Blatt, M Krüger, T Ziebart, K Sagheb… - Journal of Cranio …, 2017 - Elsevier
Oral squamous cell carcinoma (OSCC) represents the sixth most common cancer,
accounting for 2–4% of all malignancies worldwide. The overall survival rate of less than …
accounting for 2–4% of all malignancies worldwide. The overall survival rate of less than …