The intestinal barrier as an emerging target in the toxicological assessment of mycotoxins

P Akbari, S Braber, S Varasteh, A Alizadeh… - Archives of …, 2017 - Springer
Mycotoxins, the secondary metabolites of fungal species, are the most frequently occurring
natural food contaminants in human and animal diets. Risk assessment of mycotoxins …

Impact of mycotoxins on the intestine: are mucus and microbiota new targets?

H Robert, D Payros, P Pinton, V Theodorou… - Journal of Toxicology …, 2017 - Taylor & Francis
There is an increasing awareness of the deleterious effects attributed to mycotoxins during
their fate within the gut, particularly for deoxynivalenol (DON), zearalenone (ZEN) …

Risk assessment of ochratoxin A in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA to update their 2006 opinion on ochratoxin
A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and …

Bioactivity of polyphenols: preventive and adjuvant strategies toward reducing inflammatory bowel diseases—promises, perspectives, and pitfalls

A Kaulmann, T Bohn - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Inflammatory bowel diseases (IBDs) are characterized by autoimmune and inflammation‐
related complications of the large intestine (ulcerative colitis) and additional parts of the …

[HTML][HTML] Zinc and gastrointestinal disease

S Skrovanek, K DiGuilio, R Bailey… - World journal of …, 2014 - ncbi.nlm.nih.gov
This review is a current summary of the role that both zinc deficiency and zinc
supplementation can play in the etiology and therapy of a wide range of gastrointestinal …

Substances for reduction of the contamination of feed by mycotoxins: A review

A Kolosova, J Stroka - World Mycotoxin Journal, 2011 - wageningenacademic.com
The global occurrence of mycotoxins is considered to be a major risk factor for human and
animal health. Contamination of different agricultural commodities with mycotoxins still …

Some food-associated mycotoxins as potential risk factors in humans predisposed to chronic intestinal inflammatory diseases

M Maresca, J Fantini - Toxicon, 2010 - Elsevier
Mycotoxins are fungal metabolites able to affect the functions of numerous tissues and
organs in animals and humans, including intestinal and immune systems. However, the …

Modulation of intestinal epithelial permeability in differentiated Caco-2 cells exposed to aflatoxin M1 and ochratoxin A individually or collectively

Y Gao, S Li, J Wang, C Luo, S Zhao, N Zheng - Toxins, 2017 - mdpi.com
Aflatoxin M1 (AFM1) and ochratoxin A (OTA) are mycotoxins commonly found in milk;
however, their effects on intestinal epithelial cells have not been reported. In the present …

Effects of curcumin on performance, antioxidation, intestinal barrier and mitochondrial function in ducks fed corn contaminated with ochratoxin A

D Ruan, WC Wang, CX Lin, AM Fouad, W Chen… - Animal, 2019 - cambridge.org
Curcumin has been attributed with antioxidant, anti-inflammatory, antibacterial activities, and
has shown highly protective effects against enteropathogenic bacteria and mycotoxins …

[HTML][HTML] Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes

KH Han, N Hashimoto, M Fukushima - World journal of …, 2016 - ncbi.nlm.nih.gov
Excessive consumption of alcoholic beverages is a serious cause of liver disease
worldwide. The metabolism of ethanol generates reactive oxygen species, which play a …