Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico

I Silva-Zolezzi, A Hidalgo-Miranda… - Proceedings of the …, 2009 - National Acad Sciences
Mexico is developing the basis for genomic medicine to improve healthcare of its population.
The extensive study of genetic diversity and linkage disequilibrium structure of different …

A functional promoter polymorphism in monocyte chemoattractant protein–1 is associated with increased susceptibility to pulmonary tuberculosis

PO Flores-Villanueva, JA Ruiz-Morales… - The Journal of …, 2005 - rupress.org
We examined the distribution of single nucleotide polymorphisms (SNPs) in nitric oxide
synthase 2A, monocyte chemoattractant protein–1 (MCP-1), regulated on activation, normal …

Pre‐Hispanic Mesoamerican demography approximates the present‐day ancestry of Mestizos throughout the territory of Mexico

R Rubi‐Castellanos, G Martínez‐Cortés… - American Journal of …, 2009 - Wiley Online Library
Over the last 500 years, admixture among Amerindians, Europeans, and Africans,
principally, has come to shape the present‐day gene pool of Mexicans, particularly …

Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping

C Bonilla, EJ Parra, CL Pfaff, S Dios… - Annals of human …, 2004 - Wiley Online Library
Hispanic populations are a valuable resource that can and should facilitate the identification
of complex trait genes by means of admixture mapping (AM). In this paper we focus on a …

Admixture in Mexico City: implications for admixture mapping of type 2 diabetes genetic risk factors

VL Martinez-Marignac, A Valladares, E Cameron… - Human genetics, 2007 - Springer
Admixture mapping is a recently developed method for identifying genetic risk factors
involved in complex traits or diseases showing prevalence differences between major …

Genetic admixture, relatedness, and structure patterns among Mexican populations revealed by the Y‐chromosome

H Rangel‐Villalobos, JF Muñoz‐Valle… - American Journal of …, 2008 - Wiley Online Library
Y‐linked markers are suitable loci to analyze genetic diversity of human populations,
offering knowledge of medical, forensic, and anthropological interest. In a population sample …

Admixture analysis of a rural population of the state of Guerrero, Mexico

C Bonilla, G Gutiérrez, EJ Parra, C Kline… - American Journal of …, 2005 - Wiley Online Library
We studied 156 individuals of Native American descent from the city of Tlapa in the state of
Guerrero in western Mexico. Most individuals' ethnicity was either Nahua, Mixtec, or …

Evidence for Common Ancestral Origin of a Recurring BRCA1 Genomic Rearrangement Identified in High-Risk Hispanic Families

JN Weitzel, VI Lagos, JS Herzog, T Judkins… - … Biomarkers & Prevention, 2007 - AACR
Background: Large rearrangements account for 8% to 15% of deleterious BRCA mutations,
although none have been characterized previously in individuals of Mexican ancestry …

[HTML][HTML] Interethnic variability and admixture in Latin America-social implications

FM Salzano - Revista de biología tropical, 2004 - scielo.sa.cr
Past and present attempts to classify and characterize the human biological variability are
examined, considering the race concept, ethnic identification problems, assortative mating …

[图书][B] Genómica mestiza: Raza, nación y ciencia en Latinoamérica

CL Beltrán, P Wade, E Restrepo, RV Santos - 2017 - books.google.com
Genómica mestiza nos presenta una serie de investigaciones donde se estudia la raza y lo
mestizo. Considerando las investigaciones en los laboratorios de México, Brasil y …