In mammals, fertilization occurs via a comprehensive progression of events. Freshly
ejaculated sperm have yet to acquire progressive motility or fertilization ability. They must …

Mitogen-activated protein kinase (MAPK) is a family of Ser/Thr protein kinases that are
widely distributed in eukaryotic cells. Studies in the last decade revealed that MAPK …

This study investigated the participation of MAPK in the resumption of meiosis [germinal
vesicle breakdown (GVB)] in oocytes and cumulus expansion using oocyte-cumulus cell …

Oocyte meiotic maturation is one of the important physiological requirements for species
survival. However, little is known about the detailed events occurring during this process. A …

The spectrum of vitamin D (VD)-mediated effects has expanded in recent years, and VD is
now recognized as a versatile signaling molecule rather than being solely a regulator of …

Previous studies have found that smoking is associated with decreased male fertility via
altering the quality of semen. However, the mechanism by which cigarette smoking affects …

Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling
pathways that play essential roles in transducing extracellular environmental signals into …

Mitogen-activated protein kinases (MAPKs) are important regulators of many cellular
processes. In mammalian testes, these kinases are involved in controlling cell division …

The role of microfilaments, microtubules, and mitogen-activated protein (MAP) kinase in
regulation of several important dynamic events of porcine oocyte maturation and fertilization …

High expression of PKC-MAPK pathway mRNAs correlates with glomerular lesions in
human diabetic nephropathy. Background Activation of protein kinase C (PKC) is a major …