Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …

In vivo studies on the pathology of gestation, including preeclampsia, often use small
mammals such as rabbits or rodents, ie, mice, rats, hamsters, and guinea pigs. The key …

Preeclampsia and gestational hypertension are common complications of pregnancy
associated with significant maternal and infant morbidity. Despite extensive research …

Human umbilical cord mesenchymal stem cells (MSCs) have been reported to improve the
migration and invasion of trophoblast cells; however, little is known about whether MSC …

Placental trophoblast cells invasion into the maternal uterus is an essential and complex
event in the formation of the maternal–fetal interface. Commonly used two-dimensional (2D) …

Bisphenol-A (BPA) is a common environmental toxicant that is known to be associated with
fetal growth restriction (FGR). However, the mechanisms of how BPA induce FGR is poorly …

Background Though a large number of pregnant females have been affected by COVID-19,
there is a dearth of information on the effects of SARS-CoV-2 infection on trophoblast …

The rat possesses hemochorial placentation with deep intrauterine trophoblast cell invasion
and trophoblast-guided uterine spiral artery remodeling, which resembles human …

Maternal exercise during pregnancy has emerged as a potentially promising approach to
protect offspring from cardiovascular disease, including hypertension. Although endothelial …

Fetal growth restriction (FGR) is one of the most common complications of an abnormal
pregnancy. Placental dysplasia has been established as a significant contributing factor to …