[HTML][HTML] Interactions of SARS-CoV-2 with the blood–brain barrier

MA Erickson, EM Rhea, RC Knopp… - International Journal of …, 2021 - mdpi.com
Emerging data indicate that neurological complications occur as a consequence of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …

Structural brain changes associated with overweight and obesity

E Gómez-Apo, A Mondragón-Maya… - Journal of …, 2021 - Wiley Online Library
Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

KL Miller, F Alfaro-Almagro, NK Bangerter… - Nature …, 2016 - nature.com
Medical imaging has enormous potential for early disease prediction, but is impeded by the
difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to …

Obesity: overview of an epidemic

NS Mitchell, VA Catenacci, HR Wyatt… - Psychiatric …, 2011 - psych.theclinics.com
The obesity epidemic in the United States continues. In the last few years, obesity rates have
not increased significantly in some US subpopulations, but it is too soon to tell whether this …

[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

[HTML][HTML] Energy intake and exercise as determinants of brain health and vulnerability to injury and disease

MP Mattson - Cell metabolism, 2012 - cell.com
Evolution favored individuals with superior cognitive and physical abilities under conditions
of limited food sources, and brain function can therefore be optimized by intermittent dietary …

[HTML][HTML] Obesity associated with increased brain age from midlife

L Ronan, AF Alexander-Bloch, K Wagstyl, S Farooqi… - Neurobiology of …, 2016 - Elsevier
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …

Connectometry: A statistical approach harnessing the analytical potential of the local connectome

FC Yeh, D Badre, T Verstynen - Neuroimage, 2016 - Elsevier
Here we introduce the concept of the local connectome: the degree of connectivity between
adjacent voxels within a white matter fascicle defined by the density of the diffusing spins …

Obesity and dementia: adipokines interact with the brain

IAC Arnoldussen, AJ Kiliaan, DR Gustafson - European …, 2014 - Elsevier
Obesity is a pandemic and a serious global health concern. Obesity is a risk factor for
multiple conditions and contributes to multi-morbidities, resulting in increased health costs …

Compromised white matter integrity in obesity

S Kullmann, F Schweizer, R Veit, A Fritsche… - Obesity …, 2015 - Wiley Online Library
Obesity is associated with both structural and functional changes of the central nervous
system. While gray matter alterations in obesity point to a consistent reduction with …