Objectives Recent advances in systemic sclerosis (SSc) show that it involves a T-helper type-
2-oriented immune response with interleukin (IL)-4 and IL-13. Romilkimab is an engineered …

Objective To investigate whether nailfold videocapillaroscopy (NVC), an increasingly
worldwide used non-invasive tool to reliably evaluate the peripheral microcirculation, may …

Abstract Undifferentiated Connective Tissue Disease at risk for Systemic Sclerosis (UCTD-
risk-SSc), otherwise referred to as very early-early SSc (very early-early diagnosis of …

Pulmonary Arterial Hypertension (PAH) is a severe complication of Connective Tissue
Disease (CTD), with remarkable morbidity and mortality. However, the molecular and …

Objective The course of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is
highly variable and different from continuously progressive idiopathic pulmonary fibrosis …

Systemic sclerosis (SSc) is considered one of the most challenging and difficult to treat
among rheumatic disorders, due to its severity, multiorgan manifestation and different …

ABSTRACT Introduction: Systemic sclerosis (SSc) is associated with a heightened cancer
risk compared to the general population. Several pathways including immune system …

Objective: To evaluate the clinical efficacy of thalidomide in patients with systemic sclerosis-
associated interstitial lung disease. Methods: Ninety-six systemic sclerosis-associated …

Abstract Objective Systemic sclerosis (SSc) is an autoimmune disease the prevalence of
which varies among populations. We analyzed SSc patients from Guangxi to improve the …

Systemic sclerosis (SSc) is a rare autoimmune condition with complex pathogenesis
characterized by a heterogeneous presentation and different disease courses. Fibrosis of …