Phenolic acids and prevention of cognitive decline: Polyphenols with a neuroprotective role in cognitive disorders and Alzheimer's disease

G Caruso, J Godos, A Privitera, G Lanza, S Castellano… - Nutrients, 2022 - mdpi.com
Cognitive impairment, also known as cognitive decline, can occur gradually or suddenly and
can be temporary or more permanent. It represents an increasingly important public health …

Natural products attenuate PI3K/Akt/mTOR signaling pathway: A promising strategy in regulating neurodegeneration

S Fakhri, A Iranpanah, MM Gravandi, SZ Moradi… - Phytomedicine, 2021 - Elsevier
Background As common, progressive, and chronic causes of disability and death,
neurodegenerative diseases (NDDs) significantly threaten human health, while no effective …

[HTML][HTML] Beneficial attributes and adverse effects of major plant-based foods anti-nutrients on health: A review

H Nath, M Samtiya, T Dhewa - Human Nutrition & Metabolism, 2022 - Elsevier
Anti-nutrients are the biomolecules that if present in food along with nutrients, can reduce
either the absorption or the utilization of nutrients. The physiological importance of anti …

Novel luteolin-loaded chitosan decorated nanoparticles for brain-targeting delivery in a sporadic Alzheimer's disease mouse model: focus on antioxidant, anti …

H Abbas, NSE Sayed, NAHA Youssef, P ME Gaafar… - Pharmaceutics, 2022 - mdpi.com
Preparation and evaluation of a non-invasive intranasal luteolin delivery for the
management of cognitive dysfunction in Alzheimer's disease (AD) using novel chitosan …

Ultrasmall iron‐gallic acid coordination polymer nanodots with antioxidative neuroprotection for PET/MR imaging‐guided ischemia stroke therapy

Y Du, Y Huo, Q Yang, Z Han, L Hou, B Cui, K Fan… - …, 2023 - Wiley Online Library
Oxidative stress from reactive oxygen species (ROS) is a reperfusion injury factor that can
lead to cell damage and death. Here, ultrasmall iron‐gallic acid coordination polymer …

[HTML][HTML] Taming neuroinflammation in Alzheimer's disease: The protective role of phytochemicals through the gut− brain axis

Y Kim, J Lim, J Oh - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Alzheimer's disease (AD) is a progressive degenerative neurological condition
characterized by cognitive decline, primarily affecting memory and logical thinking, attributed …

Andrographolide attenuates short-term spatial and recognition memory impairment and neuroinflammation induced by a streptozotocin rat model of Alzheimer's …

LC Souza, MK Andrade, EM Azevedo, DC Ramos… - Neurotoxicity …, 2022 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder clinically manifested by a gradual
cognitive decline. Intracerebroventricular injection (ICV) of streptozotocin (STZ), a model of …

Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

Natural phenolic compounds with neuroprotective effects

M Tavan, P Hanachi, M de la Luz Cádiz-Gurrea… - Neurochemical …, 2024 - Springer
Neurodegenerative disorders are characterized by mitochondrial dysfunction and
subsequently oxidative stress, inflammation, and apoptosis that contribute to neuronal …

Exendin-4 prevents memory loss and neuronal death in rats with sporadic Alzheimer-like disease

AM Zago, FB Carvalho, FL Rahmeier, M Santin… - Molecular …, 2024 - Springer
This study investigated the neuroprotective effects of exendin-4 (EXE-4), an analog of the
glucagon-like peptide 1 receptor (GLP-1R) on memory and on the neuronal populations that …