Genetic and molecular epidemiology of adult diffuse glioma
AM Molinaro, JW Taylor, JK Wiencke… - Nature Reviews …, 2019 - nature.com
The WHO 2007 glioma classification system (based primarily on tumour histology) resulted
in considerable interobserver variability and substantial variation in patient survival within …
in considerable interobserver variability and substantial variation in patient survival within …
Classification of adult‐type diffuse gliomas: Impact of the World Health Organization 2021 update
BT Whitfield, JT Huse - Brain pathology, 2022 - Wiley Online Library
Over the last decade, developments in molecular profiling have radically altered the
diagnosis, classification, and management of numerous cancer types, with primary brain …
diagnosis, classification, and management of numerous cancer types, with primary brain …
cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas
The diagnostic importance of IDH mutational status in diffuse gliomas was first formally
recognized within the updated 4th edition of the WHO Classification of Tumours of the …
recognized within the updated 4th edition of the WHO Classification of Tumours of the …
Clinical practice guidelines for the management of adult diffuse gliomas
To follow the revision of the fourth edition of WHO classification and the recent progress on
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …
cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
The World Health Organization (WHO) central nervous system tumor classification
represents the primary source of updates on diagnostic classes, grades and criteria [17] …
represents the primary source of updates on diagnostic classes, grades and criteria [17] …
Novel, improved grading system (s) for IDH-mutant astrocytic gliomas
M Shirahata, T Ono, D Stichel, D Schrimpf… - Acta …, 2018 - Springer
Abstract According to the 2016 World Health Organization Classification of Tumors of the
Central Nervous System (2016 CNS WHO), IDH-mutant astrocytic gliomas comprised WHO …
Central Nervous System (2016 CNS WHO), IDH-mutant astrocytic gliomas comprised WHO …
CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDH-mutant gliomas
Abstract Background The 2016 World Health Organization (WHO) classification of central
nervous system tumors stratifies isocitrate dehydrogenase (IDH)–mutant gliomas into 2 …
nervous system tumors stratifies isocitrate dehydrogenase (IDH)–mutant gliomas into 2 …
[HTML][HTML] Grading of adult diffuse gliomas according to the 2021 WHO Classification of Tumors of the Central Nervous System
T Komori - Laboratory Investigation, 2022 - Elsevier
The grading of gliomas based on histological features has been a subject of debate for
several decades. A consensus has not yet been reached because of technical limitations …
several decades. A consensus has not yet been reached because of technical limitations …
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
Mutations affecting isocitrate dehydrogenase (IDH) enzymes are prevalent in glioma,
leukemia, and other cancers. Although mutant IDH inhibitors are effective against leukemia …
leukemia, and other cancers. Although mutant IDH inhibitors are effective against leukemia …
TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma
K Fujimoto, H Arita, K Satomi, K Yamasaki… - Acta …, 2021 - Springer
Abstract The Consortium to Inform Molecular and Practical Approaches to CNS Tumor
Taxonomy (cIMPACT-NOW) update 3 recommends that histologic grade II and III IDH …
Taxonomy (cIMPACT-NOW) update 3 recommends that histologic grade II and III IDH …