Rational design and development of SARS-CoV-2 serological diagnostics by immunoprecipitation-targeted proteomics

Z Fu, Y Rais, D Dara, D Jackson… - Analytical …, 2022 - ACS Publications
Current design of serological tests utilizes conservative immunoassay approaches and is
focused on fast and convenient assay development, throughput, straightforward …

Identification and quantification of human relaxin proteins by immunoaffinity-mass spectrometry

Y Rais, AP Drabovich - Journal of Proteome Research, 2024 - ACS Publications
The human relaxins belong to the Insulin/IGF/Relaxin superfamily of peptide hormones, and
their physiological function is primarily associated with reproduction. In this study, we …

Different metabolomic and proteomic profiles of cerebrospinal fluid in ventricular and lumbar compartments in relation to leptomeningeal metastases

JW Kwon, JH Im, KY Lee, BC Yoo, JH Lee, KH Kim… - Metabolites, 2022 - mdpi.com
The different molecular profiles of cerebrospinal fluid (CSF) between ventricular and lumbar
compartments remain elusive, especially in the context of leptomeningeal metastasis (LM) …

Mass Spectrometry-based assay for Targeting fifty-two proteins of Brain Origin in Cerebrospinal Fluid

I Batruch, B Lim, A Soosaipillai, D Brinc… - Journal of proteome …, 2020 - ACS Publications
Cerebrospinal fluid (CSF) is a circulatory fluid of the central nervous system and it can reflect
the biochemical changes occurring in the brain. Although CSF retrieval through lumbar …

Immunoprecipitation-targeted proteomics assays facilitate rational development of SARS-CoV-2 serological diagnostics

Z Fu, Y Rais, AP Drabovich - medRxiv, 2021 - medrxiv.org
Current design of serological tests employs conservative immunoassay approaches and is
often focused on convenience, speed of manufacturing, and affordability. Limitations of such …