Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics

A Hollmann, M Martinez, P Maturana… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

Escherichia coli in Europe: An Overview

N Allocati, M Masulli, MF Alexeyev, C Di Ilio - International journal of …, 2013 - mdpi.com
Escherichia coli remains one of the most frequent causes of several common bacterial
infections in humans and animals. E. coli is the prominent cause of enteritis, urinary tract …

Machine learning prediction of antimicrobial peptides

G Wang, II Vaisman, ML van Hoek - Computational peptide science …, 2022 - Springer
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …

Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity

TP Zanos, HA Silverman, T Levy… - Proceedings of the …, 2018 - National Acad Sciences
The nervous system maintains physiological homeostasis through reflex pathways that
modulate organ function. This process begins when changes in the internal milieu (eg …

Antimicrobial peptides: an alternative for innovative medicines?

JP Da Costa, M Cova, R Ferreira, R Vitorino - Applied microbiology and …, 2015 - Springer
Antimicrobial peptides are small molecules with activity against bacteria, yeasts, fungi,
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …

Mycobacterium tuberculosis cell-wall and antimicrobial peptides: a mission impossible?

YM Jacobo-Delgado, A Rodríguez-Carlos… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …

Vitamin D Induces Interleukin-1β Expression: Paracrine Macrophage Epithelial Signaling Controls M. tuberculosis Infection

M Verway, M Bouttier, TT Wang, M Carrier… - PLoS …, 2013 - journals.plos.org
Although vitamin D deficiency is a common feature among patients presenting with active
tuberculosis, the full scope of vitamin D action during Mycobacterium tuberculosis (Mtb) …

Host-directed therapeutic strategies for tuberculosis

A Kolloli, S Subbian - Frontiers in medicine, 2017 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality in humans worldwide. Currently, the standard treatment for TB …

Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review

SHE Kaufmann, C Lange, M Rao, KN Balaji… - The Lancet …, 2014 - thelancet.com
Tuberculosis continues to kill 1· 4 million people annually. During the past 5 years, an
alarming increase in the number of patients with multidrug-resistant tuberculosis and …

Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections

S Alharthi, SE Alavi, PM Moyle, ZM Ziora - Drug Discovery Today, 2021 - Elsevier
Virulence factor, sortase A (SrtA), has crucial roles in the pathogenesis of Gram-positive
superbugs. SrtA is a bacterial cell membrane enzyme that anchors crucial virulence factors …