Promoters serve a critical role in establishing baseline transcriptional capacity through the
recruitment of proteins, including transcription factors. Previously, a paucity of data for cis …

We present a physics-based machine learning approach to predict in vitro transcription
factor binding affinities from structural and mechanical DNA properties directly derived from …

The MADS transcription factors (TF) are an ancient eukaryotic protein family. In plants, the
family is divided into two main lineages. Here, we demonstrate that DNA binding in both …

Crop breeding entails developing and selecting plant varieties with improved agronomic
traits. Modern molecular techniques, such as genome editing, enable more efficient …

It was previously shown that DNA breathing, thermodynamic stability, as well as
transcriptional activity and transcription factor (TF) bindings are functionally correlated. To …

MADS transcription factors cooperate: complexities of complex formation | Journal of
Experimental Botany | Oxford Academic Skip to Main Content Advertisement Oxford …

A major question in plant biology is to understand how plant growth, development, and
environmental responses are controlled and coordinated by the activities of regulatory …

Recent efforts to sequence the genomes and transcriptomes of several gymnosperm
species have revealed an increased complexity in certain gene families in gymnosperms as …

Homeodomain transcription factors (TFs) bind to specific DNA sequences to regulate the
expression of target genes. Structural work has provided insight into molecular identities and …

Key message We studied the DNA-binding profile of the MADS-domain transcription factor
SEPALLATA3 and mutant variants by SELEX-seq. DNA-binding characteristics of …