An umbrella review of the evidence linking oral health and systemic noncommunicable diseases

J Botelho, P Mascarenhas, J Viana, L Proença… - Nature …, 2022 - nature.com
Oral diseases are highly prevalent worldwide. Recent studies have been supporting a
potential bidirectional association of oral diseases with systemic noncommunicable …

Bidirectional association between periodontal disease and diabetes mellitus: a systematic review and meta-analysis of cohort studies

J Stöhr, J Barbaresko, M Neuenschwander… - Scientific Reports, 2021 - nature.com
Periodontal disease has been reported to be associated with diabetes mellitus. However,
the direction of the association and the influence of bias are not clear. Thus, the aim of this …

[HTML][HTML] Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

X Li, H Wang, X Yu, G Saha, L Kalafati, C Ioannidis… - Cell, 2022 - cell.com
Bone marrow (BM)-mediated trained innate immunity (TII) is a state of heightened immune
responsiveness of hematopoietic stem and progenitor cells (HSPC) and their myeloid …

Global prevalence of periodontal disease and lack of its surveillance

M Nazir, A Al-Ansari, K Al-Khalifa… - The Scientific World …, 2020 - Wiley Online Library
Background. Periodontal disease is a public health problem and is strongly associated with
systemic diseases; however, its worldwide distribution is not fully understood. Objective. To …

Oral diseases: a global public health challenge

MA Peres, LMD Macpherson, RJ Weyant, B Daly… - The Lancet, 2019 - thelancet.com
Oral diseases are among the most prevalent diseases globally and have serious health and
economic burdens, greatly reducing quality of life for those affected. The most prevalent and …

Global, regional, and national prevalence, incidence, and disability-adjusted life years for oral conditions for 195 countries, 1990–2015: a systematic analysis for the …

NJ Kassebaum, AGC Smith, E Bernabé… - Journal of dental …, 2017 - journals.sagepub.com
The Global Burden of Disease 2015 study aims to use all available data of sufficient quality
to generate reliable and valid prevalence, incidence, and disability-adjusted life year (DALY) …

Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action

MS Tonetti, S Jepsen, L Jin… - Journal of clinical …, 2017 - Wiley Online Library
Background The global burden of periodontal diseases remains high. Population growth
trends, changes in risk factors and improved tooth retention will increase the socio …

Management of deep caries and the exposed pulp

L Bjørndal, S Simon, PL Tomson… - International …, 2019 - Wiley Online Library
Caries prevalence remains high throughout the world, with the burden of disease
increasingly affecting older and socially disadvantaged groups in Western cultures. If left …

Global-, regional-, and country-level economic impacts of dental diseases in 2015

AJ Righolt, M Jevdjevic… - Journal of dental …, 2018 - journals.sagepub.com
Up-to-date information about the economic impact of dental diseases is essential for health
care decision makers when seeking to make rational use of available resources. The …

Quercetin‐loaded ceria nanocomposite potentiate dual‐directional immunoregulation via macrophage polarization against periodontal inflammation

Y Wang, C Li, Y Wan, M Qi, Q Chen, Y Sun, X Sun… - Small, 2021 - Wiley Online Library
Macrophage polarization toward M1 phenotype (pro‐inflammation) is closely associated
with the destructive phase of periodontal inflammation. Nanoceria is verified to inhibit M1 …