Thiazoles have attracted much synthetic interest due to their wide variety of biological
properties and are important members of heterocyclic compounds. In recent years, studies …

Mitochondria-targeted mild-temperature photothermal therapy (MT-PTT) is a promising
strategy that can maximize anticancer effects and reduce adverse reactions. Here, a novel …

N, N‐Dimethylformamide dimethyl acetal (DMF‐DMA) reagent can react with different
functional groups of organic compounds. Enamines and dimethylamino imines are obtained …

The primary objective of the present work is to correlate the hydrogen explosive
characteristics with internal combustion engine design parameters particularly the engine …

Combined chemotherapy is recommended strategy as a first-line treatment method in
patients with cervical cancer. Ganetespib (STA-9090) is a second-generation heat shock …

Abstract Heat shock protein 90 (Hsp90) is a key chaperone that is abnormally expressed in
cancer cells, and therefore, designing novel compounds to inhibit chaperone activities of the …

Mutations of cystic fibrosis transmembrane conductance regulator (CFTR) cause cystic
fibrosis, the most common life-limiting recessive genetic disease among Caucasians. CFTR …

An efficient method for synthesising NMDAR co-agonist Sunifiram (DM235), in addition to
Sunifram-carbamate and anthranilamide hybrids, has been developed in high yields via …

Osteosarcoma is common childhood tumour type of the bone. Chemotherapy is the most
important step in treatment of osteosarcoma. Despite advanced diagnosis methods and …

Abstract Heat shock protein 90 (HSP90), as a molecular chaperone, regulates hundreds of
protein clients under both physiological and stress conditions in eukaryotic cells. However …