Update on the pathogenesis of chronic obstructive pulmonary disease

A Agustí, JC Hogg - New England Journal of Medicine, 2019 - Mass Medical Soc
Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Therapeutic targets in lung tissue remodelling and fibrosis

G Liu, AM Philp, T Corte, MA Travis, H Schilter… - Pharmacology & …, 2021 - Elsevier
Structural changes involving tissue remodelling and fibrosis are major features of many
pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and …

Polystyrene microplastic particles: In vitro pulmonary toxicity assessment

CD Dong, CW Chen, YC Chen, HH Chen… - Journal of hazardous …, 2020 - Elsevier
Microplastics (MPs) have become a global environmental concern. Recent studies have
shown that MPs, of which the predominant type is often polystyrene (PS; known as PS-MPs) …

Quantitative chest CT assessment of small airways disease in post-acute SARS-CoV-2 infection

JL Cho, R Villacreses, P Nagpal, J Guo, AA Pezzulo… - Radiology, 2022 - pubs.rsna.org
Background The long-term effects of SARS-CoV-2 infection on pulmonary structure and
function remain incompletely characterized. Purpose To test whether SARS-CoV-2 infection …

Lung function trajectories in health and disease

A Agusti, R Faner - The Lancet Respiratory Medicine, 2019 - thelancet.com
The normal lung function trajectory from birth to death has three phases: a growth phase
(from birth to early adulthood), a plateau phase (that lasts for a few years), and a decline …

Airway mucin concentration as a marker of chronic bronchitis

M Kesimer, AA Ford, A Ceppe… - … England Journal of …, 2017 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic
bronchitic and emphysematous components. In one biophysical model, the concentration of …

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary

J Vestbo, SS Hurd, AG Agustí, PW Jones… - American journal of …, 2013 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a global health problem, and since 2001,
the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published its strategy …

Airway mucus function and dysfunction

JV Fahy, BF Dickey - New England journal of medicine, 2010 - Mass Medical Soc
Pulmonary defense against environmental injury depends on airway mucus, which traps
inhaled toxins that are then cleared from the lungs by ciliary beating and cough. This review …

Particulate matter air pollution and respiratory impact on humans and animals

C Losacco, A Perillo - Environmental Science and Pollution Research, 2018 - Springer
Air pollution is now fully acknowledged to be a public health problem and a social issue.
Particulate matter (PM) concentration has been linked with several clinical manifestations of …

Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model

M Selman, A Pardo - American journal of respiratory and critical …, 2014 - atsjournals.org
A growing body of evidence indicates that aberrant activation of alveolar epithelial cells and
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …