Mitochondrial β-oxidation of fatty acids generates acetyl-coA, NADH and FADH 2. Acyl-coA
synthetases catalyze the binding of fatty acids to coenzyme A to form fatty acyl-coA …

Flavin-based electron bifurcation is a newly discovered mechanism, by which a hydride
electron pair from NAD (P) H, coenzyme F420H2, H2, or formate is split by flavoproteins into …

Apart from its main function in the mitochondria as a key element in electron transport,
Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant …

Driver mutations in oncogenic pathways, rewiring of cellular metabolism and altered ROS
homoeostasis are intimately connected hallmarks of cancer. Electrons derived from different …

Extensively revised, the fourth edition of this highly successful book takes into account the
many newly determined protein structures that provide molecular insight into chemiosmotic …

Reactive oxygen species (ROS) are highly reactive reduced oxygen molecules that result
from aerobic metabolism. The common forms are the superoxide anion (O2∙−) and hydrogen …

Mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) is not included in the
traditional textbook schemes of the respiratory chain, reflecting the fact that it is a non …

Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an
accessible, inexpensive therapeutic intervention that can improve mitochondrial …

In cellular circumstances under which carbohydrates are scarce, plants can metabolize
proteins and lipids as alternative respiratory substrates. Respiration of protein is less …

It has been long recognized that cancer cells reprogram their metabolism under hypoxia
conditions due to a shift from oxidative phosphorylation (OXPHOS) to glycolysis in order to …