Viral infections are among the most complex medical problems and have been a major
threat to the economy and global health. Several epidemics and pandemics have occurred …

Covering: 2013. Previous review: Nat. Prod. Rep., 2015, 29, 1028–1065 This review covers
the isolation and structure determination of triterpenoids reported during 2013 including …

Momordica charantia L. var. abbreviata Ser.(Mca), known as bitter gourd or bitter melon, is a
Momordica variety with medicinal value and belongs to the Cucurbitaceae family. In view of …

Arboviruses are pathogens that widely affect the health of people in different communities
around the world. Recently, a few successful approaches toward production of effective …

Introduction: There are not effective drugs available for treatment of dengue fever despite
intensive research on synthetic inhibitors. The search for active phytochemicals could serve …

Abstract Seven previously undescribed triterpenes (1–7), as well as one triterpene (8)
previously described as a synthetic product, were isolated from the antler-shaped fruiting …

Highlights•A series of novel 1, 2, 4-triazines was evaluated for Yellow fever virus
inhibition.•Several compounds displayed inhibition activities at micromolar …

Abstract The NS2B/NS3 protease is crucial for the pathogenesis of the DENV. Therefore, the
inhibition of this protease is considered to be the key strategy for the development of new …

Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis worldwide. The
emergence of new genotypes of the virus and a high rate of mutation make it necessary to …

A novel microsomes-hydrogel added cell culture system (MHCCS) was employed in the
antitumor activity screening of natural compounds, aiming to achieve drug screening with …