Gene doping: Present and future

RA Cantelmo, AP Da Silva… - European Journal of …, 2020 - Taylor & Francis
Being an elite athlete is an extremely coveted position, which can lead an individual to use
doping. As knowledge is extended, doping techniques have become increasingly …

Gene doping: an overview and current implications for athletes

T van der Gronde, O de Hon, HJ Haisma… - British Journal of Sports …, 2013 - bjsm.bmj.com
The possibility of gene doping, defined as the transfer of nucleic acid sequences and/or the
use of normal or genetically modified cells to enhance sport performance, is a real concern …

Integration of CRISPR/Cas12a and multiplexed RPA for fast detection of gene doping

J Yan, Z Xu, H Zhou, T Li, X Du, R Hu, J Zhu… - Analytical …, 2022 - ACS Publications
Fast and on-site detection is important for an effective antigene-doping strategy. However,
the current gene doping (GD) evaluation methods require sophisticated instruments and …

Control of gene doping in human and horse sports

T Tozaki, NA Hamilton - Gene therapy, 2022 - nature.com
Gene doping is prohibited in human and equine competition alike. The World Anti-Doping
Agency (WADA), Fédération Equestre Internationale (FEI) and International Federation of …

Analysis of potential gene doping preparations for transgenic DNA in the context of sports drug testing programs

N Naumann, A Paßreiter, A Thomas, O Krug… - International journal of …, 2023 - mdpi.com
Gene doping has been classified as a prohibited method by the World Anti-Doping Agency
(WADA) and the International Olympic Committee (IOC) for over two decades. As gene …

Screening for gene doping transgenes in horses via the use of massively parallel sequencing

J Maniego, B Pesko, J Habershon-Butcher, J Huggett… - Gene therapy, 2022 - nature.com
Throughout the history of horse racing, doping techniques to suppress or enhance
performance have expanded to match the technology available. The next frontier in doping …

Equine performance genes and the future of doping in horseracing

T Wilkin, A Baoutina, N Hamilton - Drug testing and analysis, 2017 - Wiley Online Library
A horse's success on the racetrack is determined by genetics, training and nutrition, and
their translation into physical traits such as speed, endurance and muscle strength …

Establishment of two quantitative nested qPCR assays targeting the human EPO transgene

EWI Neuberger, I Perez, C Le Guiner, D Moser, T Ehlert… - Gene therapy, 2016 - nature.com
For ethical and safety reasons it is critical to develop easily implemented assays with high
sensitivity and specificity for gene doping surveillance. Two nested quantitative real-time …

A duplex qPCR assay for human erythropoietin (EPO) transgene to control gene doping in horses

HW Cheung, KS Wong, VYC Lin… - Drug testing and …, 2021 - Wiley Online Library
The misuse of genetic manipulation technology to enhance athletic performance is termed
gene doping which is prohibited in human sports, horseracing, and equestrian sports …

From gene engineering to gene modulation and manipulation: can we prevent or detect gene doping in sports?

G Fischetto, S Bermon - Sports Medicine, 2013 - Springer
During the last 2 decades, progress in deciphering the human gene map as well as the
discovery of specific defective genes encoding particular proteins in some serious human …