ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum

F Reggiori, M Molinari - Physiological reviews, 2022 - journals.physiology.org
ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …

[HTML][HTML] Role and regulation of autophagy in cancer

R Rakesh, LC PriyaDharshini, KM Sakthivel… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

Natural killer–derived exosomal miR-186 inhibits neuroblastoma growth and immune escape mechanisms

P Neviani, PM Wise, M Murtadha, CW Liu, CH Wu… - Cancer research, 2019 - AACR
In neuroblastoma, the interplay between immune cells of the tumor microenvironment and
cancer cells contributes to immune escape mechanisms and drug resistance. In this study …

Hypoxia and selective autophagy in cancer development and therapy

I Daskalaki, I Gkikas, N Tavernarakis - Frontiers in cell and …, 2018 - frontiersin.org
Low oxygen availability, a condition known as hypoxia, is a common feature of various
pathologies including stroke, ischemic heart disease, and cancer. Hypoxia adaptation …

Anaplastic thyroid carcinoma: Current issues in genomics and therapeutics

I Abe, AK Lam - Current Oncology Reports, 2021 - Springer
Abstract Purpose of Review Anaplastic thyroid carcinoma is a type of thyroid carcinoma with
the most aggressive biological behaviour amongst thyroid cancer. Here, we review the …

Implications of estrogen and its receptors in colorectal carcinoma

PK Das, J Saha, S Pillai, AKY Lam, V Gopalan… - Cancer …, 2023 - Wiley Online Library
Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …

PDMDA: predicting deep-level miRNA–disease associations with graph neural networks and sequence features

C Yan, G Duan, N Li, L Zhang, FX Wu, J Wang - Bioinformatics, 2022 - academic.oup.com
Motivation Many studies have shown that microRNAs (miRNAs) play a key role in human
diseases. Meanwhile, traditional experimental methods for miRNA–disease association …

[HTML][HTML] Functions and mechanisms of miR-186 in human cancer

Z Wang, HH Sha, HJ Li - Biomedicine & Pharmacotherapy, 2019 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the post-
transcriptional level. Mounting evidence suggests the involvement of miRNAs in …

Autophagy and gastrointestinal cancers: the behind the scenes role of long non-coding RNAs in initiation, progression, and treatment resistance

R Shafabakhsh, F Arianfar, M Vosough… - Cancer Gene …, 2021 - nature.com
Gastrointestinal (GI) cancers comprise a heterogeneous group of complex disorders that
affect different organs, including esophagus, stomach, gallbladder, liver, biliary tract …

[PDF][PDF] Long intergenic non-protein coding RNA 665 regulates viability, apoptosis, and autophagy via the MiR-186-5p/MAP4K3 axis in hepatocellular carcinoma

Y Shan, P Li - Yonsei medical journal, 2019 - synapse.koreamed.org
Purpose Long intergenic non-protein coding RNA 665 (LINC00665) plays a vital role in the
development of cancer. Its function in hepatocellular carcinoma (HCC), however, remains …