Non-invasive therapeutic methods have recently been used in medical sciences. Enzymes
have shown high activity at very low concentrations in laboratories and pharmaceutical …

Peyronie's disease (PD) is most simply referred to as a fibrotic wound-healing disorder of the
tunica albuginea. It is both a physically and psychologically devastating disorder that causes …

Purpose: We validated the Peyronie's Disease Questionnaire (http://www. auxilium.
com/PDQ), a 15-question self-reported survey that measures the impact and severity of …

Objectives To examine the efficacy of intralesional collagenase Clostridium histolyticum
(CCH) in defined subgroups of patients with Peyronie's disease (PD). Patients and Methods …

Purpose: Collagenase Clostridium histolyticum is an investigational nonsurgical treatment
for Peyronie disease. In this phase 2b, double-blind, randomized, placebo controlled study …

Introduction Collagenase clostridium histolyticum (CCH; Xiaflex, Auxilium Pharmaceuticals,
Inc., Chesterbrook, PA, USA) is a Food and Drug Administration-approved, intralesional …

Abstract Introduction Patients with Peyronie's disease may experience significat distress.
The choice of treatment depends on a variety of factors, including the stage of the disease …

Introduction Extracorporeal shock wave therapy (ESWT) for treatment of Peyronie's disease
(PD) is controversial. Aim To study the efficacy of ESWT by a placebo-controlled …

Introduction Peyronie's disease (PD) is a benign fibrotic disorder of the tunica albuginea of
the penis, which can cause penile pain, curvature, shortening, erectile dysfunction, and …

The aims of the present review were to assess the literature on published outcomes and
complications associated with surgical treatments for P eyronie's disease (PD) and to assist …