Elevated cortisol in a subset of depressed patients is an enduring and well-replicated
finding. Much interest has focused on the possible effects of depression on the …

Osteoporosis is the most common metabolic bone disorder and remains an increasingly
significant problem, affecting 200 million individuals worldwide. Osteoporosis often is …

The allostatic load model proposed by McEwen and Stellar refers to the wear and tear that
the body experiences due to the repeated use of adaptive responses to stress, as well as the …

Background Selective serotonin reuptake inhibitors (SSRIs) are a widely used class of
antidepressants that block the serotonin transporter. Osteoblasts and osteocytes express …

HTT mediates antidepressant‐sensitive clearance of 5‐HT after its release into neural
synapses. We found increased expression of 5‐HTT in RANKL‐induced osteoclast‐like …

A general misapprehension exists about physical characteristics that seem to emerge as
women age. More specifically, changes such as a kyphosis or dowager's hump, a forward …

It has been shown that antidepressants would have a direct action on bone metabolism and
would be associated with increased fracture risk. Results from this large meta-analysis show …

Existing studies of the relationship between depression and osteoporosis have been
heterogeneous in their design and use of diagnostic instruments for depression, which might …

Objective: Osteoporosis occurs in common psychiatric conditions and causes significant
morbidity. Many neuroleptic medications can cause hyperprolactinemia, which can then …

Introduction There have been numerous studies examining the association between
depression and bone mineral density (BMD), but the underlying nature of this relationship …