Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

The clinical basis of orthorexia nervosa: emerging perspectives

NS Koven, AW Abry - Neuropsychiatric disease and treatment, 2015 - Taylor & Francis
Orthorexia nervosa describes a pathological obsession with proper nutrition that is
characterized by a restrictive diet, ritualized patterns of eating, and rigid avoidance of foods …

Cortical abnormalities associated with pediatric and adult obsessive-compulsive disorder: findings from the ENIGMA Obsessive-Compulsive Disorder Working Group

PSW Boedhoe, L Schmaal, Y Abe… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Brain imaging studies of structural abnormalities in OCD have yielded
inconsistent results, partly because of limited statistical power, clinical heterogeneity, and …

[图书][B] The neuroscience of psychotherapy: Healing the social brain (Norton Series on Interpersonal Neurobiology)

L Cozolino - 2017 - books.google.com
An update to the classic text that links neuroscience and human behavior in the context of
therapy. This groundbreaking book explores the recent revolution in psychotherapy that has …

Frontoparietal areas link impairments of large-scale intrinsic brain networks with aberrant fronto-striatal interactions in OCD: a meta-analysis of resting-state functional …

DA Gürsel, M Avram, C Sorg, F Brandl… - … & Biobehavioral Reviews, 2018 - Elsevier
Neuroimaging studies report evidence for two distinct pathophysiological models of
obsessive-compulsive disorder (OCD): disrupted fronto-striatal circuits and impaired large …

Development of human brain cortical network architecture during infancy

W Gao, S Alcauter, JK Smith, JH Gilmore… - Brain Structure and …, 2015 - Springer
The brain's mature functional network architecture has been extensively studied but the
early emergence of the brain's network organization remains largely unknown. In this study …

Toward a neurocircuit-based taxonomy to guide treatment of obsessive–compulsive disorder

E Shephard, ER Stern, OA van den Heuvel… - Molecular …, 2021 - nature.com
An important challenge in mental health research is to translate findings from cognitive
neuroscience and neuroimaging research into effective treatments that target the …

Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder

A Anticevic, S Hu, S Zhang, A Savic, E Billingslea… - Biological …, 2014 - Elsevier
Background Obsessive-compulsive disorder (OCD) is associated with regional hyperactivity
in cortico-striatal circuits. However, the large-scale patterns of abnormal neural connectivity …

Obsessive-compulsive disorder

WK Goodman, DE Grice, KAB Lapidus… - Psychiatric …, 2014 - psych.theclinics.com
Obsessive-compulsive disorder (OCD) is a common, typically chronic disorder marked by
intrusive and disturbing thoughts (obsessions) and repetitive behaviors (compulsions) that …

Compensatory frontoparietal activity during working memory: an endophenotype of obsessive-compulsive disorder

FE de Vries, SJ de Wit, DC Cath, YD van der Werf… - Biological …, 2014 - Elsevier
Background Subtle deficits in executive functioning are present in patients with obsessive-
compulsive disorder (OCD) and their first-degree relatives, suggesting involvement of the …