Label-free surface-enhanced Raman spectroscopy of biofluids: fundamental aspects and diagnostic applications

A Bonifacio, S Cervo, V Sergo - Analytical and bioanalytical chemistry, 2015 - Springer
In clinical practice, one objective is to obtain diagnostic information while minimizing the
invasiveness of the tests and the pain for the patients. To this end, tests based on the …

Analytical methods for quantifying creatinine within biological media

EP Randviir, CE Banks - Sensors and Actuators B: Chemical, 2013 - Elsevier
Creatinine, a molecule created within skeletal muscles as a product of work, is a widely
studied molecule within the bioanalytical field, which can be used to reflect the state of renal …

Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care

SQ Wang, X Zhao, I Khimji, R Akbas, W Qiu… - Lab on a Chip, 2011 - pubs.rsc.org
Ovarian cancer is asymptomatic in the early stages and most patients present with advanced
levels of disease. The lack of cost-effective methods that can achieve frequent, simple and …

Quantifying creatinine and urea in human urine through Raman spectroscopy aiming at diagnosis of kidney disease

CJ Saatkamp, ML de Almeida… - … of biomedical optics, 2016 - spiedigitallibrary.org
Due to their importance in the regulation of metabolites, the kidneys need continuous
monitoring to check for correct functioning, mainly by urea and creatinine urinalysis. This …

Sensitive and fast detection of fructose in complex media via symmetry breaking and signal amplification using surface-enhanced Raman spectroscopy

F Sun, T Bai, L Zhang, JR Ella-Menye, S Liu… - Analytical …, 2014 - ACS Publications
A new strategy is proposed to sensitively and rapidly detect analytes with weak Raman
signals in complex media using surface-enhanced Raman spectroscopy (SERS) via …

Reagent-and separation-free measurements of urine creatinine concentration using stamping surface enhanced Raman scattering (S-SERS)

M Li, Y Du, F Zhao, J Zeng, C Mohan… - Biomedical optics …, 2015 - opg.optica.org
We report a novel reagent-and separation-free method for urine creatinine concentration
measurement using stamping surface enhanced Raman scattering (S-SERS) technique with …

A turn-on fluorescence sensor for creatinine based on the quinoline-modified metal organic frameworks

S Qu, Q Cao, J Ma, Q Jia - Talanta, 2020 - Elsevier
Creatinine (Cre) level is closely related to renal function of human. Therefore, it is of great
significance to develop highly sensitive and selective tools for Cre determination. Herein, a …

Correlating the amount of urea, creatinine, and glucose in urine from patients with diabetes mellitus and hypertension with the risk of developing renal lesions by …

JAM Bispo, EE de Sousa Vieira… - … of biomedical optics, 2013 - spiedigitallibrary.org
Patients with diabetes mellitus and hypertension (HT) diseases are predisposed to kidney
diseases. The objective of this study was to identify potential biomarkers in the urine of …

Gold nanoparticles-based colorimetric and visual creatinine assay

Y He, X Zhang, H Yu - Microchimica acta, 2015 - Springer
We demonstrate a selective and sensitive method for determination of creatinine using
citrate-stabilized gold nanoparticles (AuNPs) as a colorimetric probe. It is based on a direct …

Ultrasensitive detection of a protein by optical trapping in a photonic‐plasmonic microcavity

MA Santiago‐Cordoba, M Cetinkaya… - Journal of …, 2012 - Wiley Online Library
Microcavity and whispering gallery mode (WGM) biosensors derive their sensitivity from
monitoring frequency shifts induced by protein binding at sites of highly confined field …