Increase of circulating inflammatory molecules in preeclampsia, an update

G Guney, MI Taskin, A Tokmak - European Cytokine Network, 2020 - Springer
Special hormonal and immunological changes are required for normal pregnancy
continuation. To escape from rejection by the maternal immune system, pregnancy needs an …

Influential Serum Kinases (Non-sFlt-1) and Phosphatases in Preeclampsia—Systematic Review and Metanalysis

KC Marrufo-Gallegos, JR Villafán-Bernal… - International Journal of …, 2023 - mdpi.com
The early identification of women with an increased risk of preeclampsia (PE) is desirable,
but apart from soluble fms-like tyrosine kinase-1 (sFlt-1), few biomarkers have previously …

Analysis of circulating microRNA signatures and preeclampsia development

ML Martinez-Fierro, I Garza-Veloz - Cells, 2021 - mdpi.com
microRNAs are important regulators of cell processes and have been proposed as potential
preeclampsia biomarkers. We evaluated serum microRNA expression profiling to identify …

The association of familial hypertension and risk of gestational hypertension and preeclampsia

M Lewandowska - International Journal of Environmental Research and …, 2021 - mdpi.com
It has not been established how history of hypertension in the father or mother of pregnant
women, combined with obesity or smoking, affects the risk of main forms of pregnancy …

AT2R activation increases in vitro angiogenesis in pregnant human uterine artery endothelial cells

JS Mishra, DB Chen, S Kumar - Plos one, 2022 - journals.plos.org
Angiogenesis is vital during pregnancy for remodeling and enhancing vasodilation of
maternal uterine arteries, and increasing uterine blood flow. Abnormal angiogenesis is …

Fibroblast growth factor type 2 (FGF2) administration attenuated the clinical manifestations of preeclampsia in a murine model induced by L-NAME

ML Martinez-Fierro, GP Hernadez-Delgadillo… - Frontiers in …, 2021 - frontiersin.org
Background: In preeclampsia, a hypertensive disorder of pregnancy, the poor remodeling of
spiral arteries leads to placental hypoperfusion and ischemia, provoking generalized …

Kidney injury molecule-1 and podocalyxin dysregulation in an arginine vasopressin induced rodent model of preeclampsia

S Ramdin, T Naicker, S Baijnath, N Govender - European Journal of …, 2023 - Elsevier
Objective To assess renal injury in an arginine vasopressin (AVP) rodent model of
preeclampsia. Study design Urinary expression of kidney injury molecule-1 (KIM-1), urinary …

New highly sensitive sandwich ELISA system for soluble endoglin quantification in different biological fluids

IV Smirnov, IV Gryazeva, MY Vasileva… - … Journal of Clinical …, 2018 - Taylor & Francis
Soluble endoglin (sEng) is a fragment of a membrane-associated receptor (CD105)
expressed on endothelial cells, mesenchymal stem cells and trophoblast cells. It is …

[HTML][HTML] MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

S Chen, L Zhang, B Feng, W Wang, D Liu… - European Journal of …, 2022 - ncbi.nlm.nih.gov
Thrombomodulin (TM) is involved in the pathological process of atherosclerosis; however,
the underlying mechanism remains unclear. Oxidised low-density lipoprotein (Ox-LDL; 100 …

Transactivation of Met signalling by semaphorin4D in human placenta: implications for the pathogenesis of preeclampsia

G Li, L Ma, H Lu, G Cao, X Shao, Y Liu, Y Li… - Journal of …, 2018 - journals.lww.com
Objective: The signalling of the receptor tyrosine kinase Met is critical in promoting
trophoblast cell invasion, and the deficiency in HGF/Met signalling is associated with …