Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Isothermal autocatalytic DNA circuits have been proven to be versatile and powerful
biocomputing platforms by virtue of their self-sustainable and self-accelerating reaction …

The wide extracellular‐intracellular distribution of microRNA requires the on‐site, robust and
efficient activation of catalytic DNA circuits inside live cells. Herein, we develop an efficient …

CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Conspectus MicroRNAs (miRNAs) are a class of small noncoding RNAs that act as pivotal
post-transcriptional regulators of gene expression, thus involving in many fundamental …

Molecular machines have previously been designed that are propelled by DNAzymes,,,
protein enzymes,, and strand displacement,,. These engineered machines typically move …

DNA and RNA nanotechnology has been used for the development of dynamic molecular
devices. In particular, programmable enzyme-free nucleic acid circuits, such as catalytic …

DNA molecular machines show great promise in fields such as biomarker discovery and
biological activity regulation, but operating DNA machines with specific functions within …