MMJ Chua, CE Ortega, A Sheikh, M Lee… - Pharmaceuticals, 2017 - mdpi.com
CK2 genes are overexpressed in many human cancers, and most often overexpression is associated with worse prognosis. Site-specific expression in mice leads to cancer …
A Yadav, B Kumar, J Datta, TN Teknos, P Kumar - Molecular cancer research, 2011 - AACR
Epithelial–mesenchymal transition (EMT) is a key process in tumor metastatic cascade that is characterized by the loss of cell–cell junctions and cell polarity, resulting in the acquisition …
Multiple genetic and epigenetic events, including the aberrant expression and function of molecules regulating cell signaling, growth, survival, motility, angiogenesis, and cell cycle …
S Trellakis, K Bruderek, CA Dumitru… - … journal of cancer, 2011 - Wiley Online Library
The progression of epithelial cancer is associated with an intense immunological interaction between the tumor cells and immune cells of the host. However, little is known about the …
Proteins of the signal transducer and activator of transcription (STAT) family mediate cellular responses to cytokines and growth factors. Aberrant regulation of the STAT3 oncogene …
R Vander Broek, S Mohan, DF Eytan, Z Chen… - Oral …, 2015 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is one of the most morbid, mortal, and genetically diverse malignancies. Although HNSCC is heterogeneous in nature, alterations …
Purpose The purpose of this study was to examine whether quality of life (QOL) scores predict survival among patients with head and neck cancer, controlling for demographic …
ME Arellano‐Garcia, S Hu, J Wang, B Henson… - Oral …, 2008 - Wiley Online Library
Objective: For clinical applications of biomarkers, there is a need for multiplex assays using high throughput platforms. The objective of this study was to determine the efficacy of …
M Hajek, A Sewell, S Kaech, B Burtness… - Cancer, 2017 - Wiley Online Library
BACKGROUND The incidence of human papillomavirus (HPV)‐associated (HPV‐positive) head and neck squamous cell carcinoma (HNSCC) of the oropharynx has dramatically …