Insulin resistance often refers to a pathological condition in which cells fail to respond to the
normal actions of insulin. Increasing literature has noted a critical role of insulin resistance in …

Background and aims Intracranial atherosclerosis (ICAS) is a predictable and preventable
condition, but existing evidence concerning its risk factors has not been quantitatively …

Background and aims Recent studies have recognized triglyceride-glucose index (TyG) as a
practical surrogate of insulin resistance. Previous studies have demonstrated that insulin …

BACKGROUND AND PURPOSE: The ongoing population-based Barcelona-Asymptomatic
Intracranial Atherosclerosis (Barcelona-AsIA) study is a prospective study that plans to …

Background and Purpose—Intracranial atherosclerotic disease (ICAD) remains a challenge
for stroke primary and secondary prevention. Molecular pathways involved in the …

Intracranial atherosclerosis is more prevalent in Asian patients, whereas extracranial
atherosclerosis is more common in individuals from western countries. The reasons for this …

Introduction The relationship between insulin resistance (IR) and cardiovascular diseases is
unclear. We aimed to examine the causal associations of IR with cardiovascular diseases …

Objective The risk of ischemic stroke with intracranial stenosis is associated with various
serum lipid levels. However, the effects of changes in the lipid profile on the risk of in-stent …

Background: Triglyceride (TG)/high-density lipoprotein cholesterol ratio (THR) is a marker of
dyslipidemia, and high THR is associated with an increase in cardiovascular events. In the …

Observational studies reveal the growing burden and adverse cerebrovascular effects of
dysglycemic states. Currently available interventional studies assessing more intensive …