The identification of ligands from large biological libraries by phage display has now been
used for almost 15 years. Most of the successful reports on high‐affinity ligand identification …

Although monoclonal antibodies have demonstrated clinical potentials as tumor targeting
agents, poor tumor penetration of the antibodies due to the size of molecules and liver/bone …

Biological and chemical weapons are a growing terrorist threat to the United States and
other nations and countermeasures continue to evolve as a national and global priority …

A novel approach to develop a peptide, that can recognize fullerene (C60) is described for
affinity selection of phage displayed peptides from a combinatorial peptide library …

Activation of the estrogen receptor alpha (ERα) is of prime importance for the development
of hormone-dependent breast cancers. Hence, drugs able to impede the emergence of an …

Novel effects of naturally occurring peptides are continuing to be discovered, and their
mechanisms of actions as well as interactions with other substances, organs, and systems …

We identified a large number of peptide mimotopes of the adrenocorticotropic hormone
(ACTH) and the α-melanocyte stimulating hormone (α-MSH) to analyze better the structure …

Biomolecular engineering has many applications in the identification of potentially
therapeutic compounds. An important class of these compounds is those that bind and …

New pharmaceutical approaches, such as biotechnology industry, genomic and proteomic
studies, require the development of new analytical and preparative tools that should allow …

Estrogen has a key role in the regulation of skeletal growth and maintenance of bone mass.
Recently, we developed peptides having estrogen-like activity as potential estrogen-based …