D-chiro-inositol glycans in insulin signaling and insulin resistance

J Larner, DL Brautigan, MO Thorner - Molecular Medicine, 2010 - Springer
Classical actions of insulin involve increased glucose uptake from the bloodstream and its
metabolism in peripheral tissues, the most important and relevant effects for human health …

D-Pinitol—active natural product from carob with notable insulin regulation

A Azab - Nutrients, 2022 - mdpi.com
Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also
been traditionally used for medicinal purposes. Carob contains many nutrients and active …

Modulation of gonadotrophin induced steroidogenic enzymes in granulosa cells by d-chiroinositol

S Sacchi, F Marinaro, D Tondelli, J Lui, S Xella… - Reproductive Biology …, 2016 - Springer
Background d-chiroinositol (DCI) is a inositolphosphoglycan (IPG) involved in several
cellular functions that control the glucose metabolism. DCI functions as second messenger …

d-Pinitol and myo-Inositol Stimulate Translocation of Glucose Transporter 4 in Skeletal Muscle of C57BL/6 Mice

NT Dang, R Mukai, K Yoshida… - Bioscience …, 2010 - academic.oup.com
Diabetes mellitus is a complex disease that is characterized by the defection of insulin
sensitivity in such peripheral tissues as skeletal muscle, adipose tissue and liver. We have …

[HTML][HTML] Inositols and metabolic disorders: From farm to bedside

M Caputo, E Bona, I Leone, MT Samà, A Nuzzo… - Journal of Traditional …, 2020 - Elsevier
Inositol and its derivates are catching interest in metabolism since taking part in several
physiological processes, including endocrine modulation. Through several mechanisms …

A review of the role of inositols in conditions of insulin dysregulation and in uncomplicated and pathological pregnancy

OC Watkins, HEJ Yong, N Sharma… - Critical Reviews in Food …, 2022 - Taylor & Francis
Inositols, a group of 6-carbon polyols, are highly bioactive molecules derived from diet and
endogenous synthesis. Inositols and their derivatives are involved in glucose and lipid …

Amperometric determination of Myo-inositol using a glassy carbon electrode modified with nanostructured copper sulfide

R Rajaram, M Kiruba, C Suresh, J Mathiyarasu… - Microchimica Acta, 2020 - Springer
A method for the amperometric determination of Myo-inositol is presented. Nanostructured
copper sulfide material was synthesized by solvothermal method and utilized as sensor …

Inositol and antioxidant supplementation: Safety and efficacy in pregnancy

G Formoso, MPA Baldassarre… - Diabetes/metabolism …, 2019 - Wiley Online Library
Pregnancies complicated by diabetes have largely increased in number over the last 50
years. Pregnancy is characterized by a physiologic increase in insulin resistance, which …

Metabolomics reveals relationship between plasma inositols and birth weight: possible markers for fetal programming of type 2 diabetes

PM Nissen, C Nebel, N Oksbjerg… - BioMed research …, 2011 - Wiley Online Library
Epidemiological studies in man and with experimental animal models have shown that
intrauterine growth restriction (IUGR) resulting in low birth weight is associated with higher …

Placental inositol reduced in gestational diabetes as glucose alters inositol transporters and IMPA1 enzyme expression

RA Pillai, MO Islam, P Selvam, N Sharma… - The Journal of …, 2021 - academic.oup.com
Context Perturbed inositol physiology in insulin-resistant conditions has led to proposals of
inositol supplementation for gestational diabetes (GDM) prevention, but placental inositol …