ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to
metastasis and therapy resistance. Owing to its aggressive nature and limited availability of …
metastasis and therapy resistance. Owing to its aggressive nature and limited availability of …
Drug-Induced Reorganisation of Lipid Metabolism Limits the Therapeutic Efficacy of Ponatinib in Glioma Stem Cells
P Aldaz, A Olias-Arjona, I Lasheras-Otero, K Ausin… - Pharmaceutics, 2024 - mdpi.com
The standard of care for glioblastoma (GBM) involves surgery followed by adjuvant radio-
and chemotherapy, but often within months, patients relapse, and this has been linked to …
and chemotherapy, but often within months, patients relapse, and this has been linked to …