Mycoplasma pneumoniae is an important cause of respiratory tract infections in children as
well as adults that can range in severity from mild to life-threatening. Over the past several …

The single gene, single protein, single function hypothesis is increasingly becoming
obsolete. Numerous studies have demonstrated that individual proteins can moonlight …

Adaption of a single protein to perform multiple independent functions facilitates functional
plasticity of the proteome allowing a limited number of protein-coding genes to perform a …

It is not often realized that the absolute protein specificity is an exception rather than a rule.
Two major kinds of protein multi-specificities are promiscuity and moonlighting. This review …

Predicting protein function has been a major goal of bioinformatics for several decades, and
it has gained fresh momentum thanks to recent community-wide blind tests aimed at …

Enzymes have been shaped by evolution over billions of years to catalyse the chemical
reactions that support life on earth. Dispersed in the literature, or organised in online …

SMC1A encodes one of the proteins of the cohesin complex. SMC1A variants are known to
cause a phenotype resembling Cornelia de Lange syndrome (CdLS). Exome sequencing …

Two major types of intercellular communication are found in the central nervous system
(CNS), namely wiring transmission (point-to-point communication, the prototype being …

Opsins, the protein moieties of animal visual photo-pigments, have emerged as
moonlighting proteins with diverse, light-dependent and-independent physiological …

The excretion of cytoplasmic and signal-peptide-less proteins (ECP) by microorganisms and
eukaryotes remains a fascinating topic. In principle, it appears to be a waste of energy …