Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the
discovery of phytocannabinoids, including the Cannabis major psychoactive compound—Δ9 …

Pain continues to be an enormous global health challenge, with millions of new untreated or
inadequately treated patients reported annually. With respect to current clinical applications …

This paper is the thirty-seventh consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2014 …

Introduction Visceral pain is a symptom reported by over 70% of inflammatory bowel disease
(IBD) sufferers. So far, a single, specific cause of this debilitating state has not been …

Epidemiological data suggest that the consumption of polyphenol-rich foods reduces the
incidence of cancer, coronary heart disease, and inflammation. Chlorogenic acid (CGA), an …

Background Inflammatory bowel disease (IBD) is a lifelong disease of the gastrointestinal
tract whose annual incidence and prevalence is on the rise. Current immunosuppressive …

The aim of our study was to investigate the effect of newly developed silver nanoparticle
aqueous suspensions NanoAg1 and NanoAg2 in the mouse models mimicking ulcerative …

AIM To investigate the therapeutic effect of hydrogen-rich water (HRW) on inflammatory
bowel disease (IBD) and to explore the potential mechanisms involved. METHODS Male …

Background and aims Molecular basis of abdominal pain in IBD is not fully characterized.
Serotonin (5-HT) increases visceral pain severity and contributes to exacerbation of …

Background: Irritable bowel syndrome (IBS) is a chronic, recurrent bowel disorder with an
unknown etiology, which is most likely multifactorial. Increased mucosal permeability …