The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Biodegradable nanocarriers such as lipid-or polymer-based nanoparticles can be designed
to improve the efficacy and reduce the toxic side effects of drugs. Under appropriate …

Squalene is a natural lipid belonging to the terpenoid family and a precursor of cholesterol
biosynthesis. It is synthesized in humans and also in a wide array of organisms and …

Nanocarriers based on polymers have attracted much attention to perform drug delivery,
especially in cancer therapy. Although significant advances have been reported, important …

Squalene is a natural triterpene and an important intermediate of sterol and hopanoid
biosynthesis in various types of cell from bacteria to human. Synthesis and further …

The functionalization and polymerization of biobased monocyclic terpenes and their
derivatives for the synthesis of sustainable polymers is described, especially in view of the …

The HIV/AIDS pandemic is an increasing global burden with devastating health-related and
socioeconomic effects. The widespread use of antiretroviral therapy has dramatically …

Nanomedicines suffer from poor drug loading and uncontrolled 'burst release'after
administration. Combining prodrug strategies with nanostructured carriers can help to …

The advent of highly active antiretroviral therapy (HAART) has significantly improved the
prognosis for human immunodeficiency virus (HIV)-infected patients, however the adverse …

Suboptimal adherence, toxicity, drug resistance and viral reservoirs make the lifelong
treatment of HIV infection challenging. The emerging field of nanotechnology may play an …