Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying
development, disease, and regeneration. As organoid research expands, the need for clear …

Recent advances in 3D cell culture technology have enabled scientists to generate stem cell
derived organoids that recapitulate the structural and functional characteristics of native …

Numerous protocols have been described for producing neural retina from human
pluripotent stem cells (hPSCs), many of which are based on the culture of 3D organoids …

Retinal development and maturation are orchestrated by a series of interacting signalling
networks that drive the morphogenetic transformation of the anterior developing brain …

In nature, cells reside in tissues subject to complex cell–cell interactions, signals from
extracellular molecules and niche soluble and mechanical signaling. These …

Retinal diseases constitute a genetically and phenotypically diverse group of clinical
conditions leading to vision impairment or blindness with limited treatment options …

Inherited retinal diseases (IRDs) cause progressive loss of light-sensitive photoreceptors in
the eye and can lead to blindness. Gene-based therapies for IRDs have shown remarkable …

An improved understanding of stem cell niches, organogenesis, and disease models has
paved the way for developing a three-dimensional (3D) organoid culture system. Organoid …

Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …

An organoid is a 3D organization of cells that can recapitulate some of the structure and
function of native tissue. Recent work has seen organoids gain prominence as a valuable …