Tight coupling between biochemical and mechanical properties of the actin cytoskeleton drives a large range of cellular processes including polarity establishment, morphogenesis …
D Wirtz - Annual review of biophysics, 2009 - annualreviews.org
A multitude of cellular and subcellular processes depend critically on the mechanical deformability of the cytoplasm. We have recently introduced the method of particle-tracking …
SH Lee, R Dominguez - Molecules and cells, 2010 - Elsevier
The dynamic remolding of the actin cytoskeleton is a critical part of most cellular activities, and malfunction of cytoskeletal proteins results in various human diseases. The transition …
BL Goode, JA Eskin, B Wendland - Genetics, 2015 - academic.oup.com
Endocytosis, the process whereby the plasma membrane invaginates to form vesicles, is essential for bringing many substances into the cell and for membrane turnover. The …
Cells use the actin cytoskeleton for many of their functions, including their division, adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …
The spectrin superfamily of proteins plays key roles in assembling the actin cytoskeleton in various cell types, crosslinks actin filaments, and acts as scaffolds for the assembly of large …
JB Moseley, BL Goode - Microbiology and Molecular Biology …, 2006 - Am Soc Microbiol
All cells undergo rapid remodeling of their actin networks to regulate such critical processes as endocytosis, cytokinesis, cell polarity, and cell morphogenesis. These events are driven …
Kinetochores are multicomponent assemblies that connect chromosomal centromeres to mitotic-spindle microtubules. The Ndc80 complex is an essential core element of …
The scaffolding protein insulin receptor tyrosine kinase substrate p53 (IRSp53), a ubiquitous regulator of the actin cytoskeleton, mediates filopodia formation under the control of Rho …