Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …

Macroautophagy/autophagy is a self-degradative process necessary for cells to maintain
their energy balance during development and in response to nutrient deprivation …

The balance of protein synthesis and degradation is finely regulated and influences cellular
homeostasis and biological processes (eg, embryonic development and neuronal plasticity) …

Macroautophagy/autophagy is an evolutionarily conserved degradation process in
eukaryotic cells that destroys obsolete proteins and damaged organelles via lysosome …

Gastrointestinal cancers are a group of cancers occurred in gastrointestinal tissues with high
morbidity and mortality rate. Although numerous studies were conducted on the …

Lung cancer is the leading cause of cancer-related mortality worldwide, with non-small cell
lung cancer (NSCLC) being the predominant type. The roles of autophagy and apoptosis in …

Autophagy regulates the formation of primary cilia, which in turn affects autophagy. The
relationship between autophagy and cilia is known to be bidirectional although the specific …

Abstract System paclitaxel-based chemotherapy is the first-line treatment regimen of
defense against breast cancer, but inherent or acquired chemotherapy resistance remains a …