Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …

Galectin-3 is a member of the galectin family, which are β‑galactoside‑binding lectins with≥
1 evolutionary conserved carbohydrate‑recognition domain. It binds proteins in a …

Bioactive peptides are specific protein fragments which, above and beyond their nutritional
capabilities, have a positive impact on the body's function or condition which may ultimately …

Highlights•Overview of the application and anti-cancer mechanisms of dietary
pectin.•Structure-activity relationships of modified pectin are discussed.•Anti-cancer …

A combination therapy approach is required to improve tumor immune infiltration and patient
response to immune checkpoint inhibitors that target negative regulatory receptors. Galectin …

Abstract Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion,
differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated …

Cellular communication events are mediated by interactions between cell-surface sugars
and lectins, which are carbohydrate-binding proteins. Galectins are β-galactosyl-binding …

Human Galectin-3 (Gal-3), a β-galactoside-binding protein expressed by tumor cells, has
been reported to act as an immune regulator in antitumor T cells. However, its effect on …

Cancer is the most common cause of human death worldwide. Conventional anticancer
therapies, including chemotherapy and radiation, are associated with severe side effects …

Studies suggest that tunicamycin may work as a therapeutic drug to cancer cells by inducing
stress in the endoplasmic reticulum (ER) through unfolded protein response (UPR) and …