Hepatocellular carcinoma (HCC) remains one of the most common and lethal malignancies
worldwide despite the development of various therapeutic strategies. A better understanding …

Cancer stem cells (CSCs) are a sub-population of cells within cancer tissues with tumor
initiation, drug resistance and metastasis properties. CSCs also have been considered as …

Cancer Stem Cells (CSCs) are a sub-population of cells, identified in most tumors,
responsible for the initiation, recurrence, metastatic potential, and resistance of different …

Background It has been proposed that cancer establishment, maintenance, and recurrence
may be attributed to a unique population of tumor cells termed cancer-initiating cells (CICs) …

Once considered a waste product of anaerobic cellular metabolism, lactate has been
identified as a critical regulator of tumorigenesis, maintenance, and progression. The …

This study reports on a microfluidic platform on which single multicellular spheroids from
malignant pleural mesothelioma (MPM), an aggressive tumor with poor prognosis, can be …

Gigartina pistillata is a red seaweed common in Figueira da Foz, Portugal. Here, the
antitumour potential of G. pistillata carrageenan, with a known variable of the life cycle, the …

Abstract Objectives Cancer stem cells (CSCs) are considered to play a pivotal role in the
process of invasion, metastasis and chemotherapy resistance. Diverse aberrantly expressed …

We previously established that COX‐2 overexpression promotes breast cancer progression
and metastasis. As long‐term use of COX‐2 inhibitors (COX‐2i) can promote thrombo …

Lung cancer is the top cause of cancer‐related deceases. One of the reasons is the
development of resistance to the chemotherapy treatment. In particular, cancer stem cells …