Oral ketamine for depression: an updated systematic review

S Meshkat, S Haikazian, JD Di Vincenzo… - The World Journal of …, 2023 - Taylor & Francis
Objectives: Ketamine is a glutamate N-methyl-D-aspartate receptor antagonist that can be
used to treat major depressive disorder by single or repeated infusions. However, the …

Beating pain with psychedelics: Matter over mind?

I Elman, A Pustilnik, D Borsook - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Basic pain research has shed light on key cellular and molecular mechanisms underlying
nociceptive and phenomenological aspects of pain. Despite these advances, we still yearn …

How does psilocybin therapy work? An exploration of experiential avoidance as a putative mechanism of change

RJ Zeifman, AC Wagner, CM Monson… - Journal of Affective …, 2023 - Elsevier
Background Psilocybin therapy is receiving attention as a mental health intervention with
transdiagnostic potential. In line with psychotherapeutic research, qualitative research has …

Chronic oral ketamine prevents anhedonia and alters neuronal activation in the lateral habenula and nucleus accumbens in rats under chronic unpredictable mild …

E Kingir, C Sevinc, G Unal - Neuropharmacology, 2023 - Elsevier
Acute injections of ketamine lead to rapid but transient antidepressant effects. Chronic oral
treatment at low doses, a promising non-invasive alternative, may prolong this therapeutic …

Wearable electronic finger for date rape drugs screening: from “do-it-yourself” fabrication to self-testing

G Poulladofonou, C Freris, A Economou… - Analytical …, 2022 - ACS Publications
In-house digital fabrication of low-cost sensors that can on-site and rapidly detect
adulteration of alcoholic beverages with sedation drugs (known as date rape drugs,(DRDs)) …

Molecular mechanisms underlying the N-methyl-d-aspartate receptor antagonists: highlighting their potential for transdiagnostic therapeutics

C Driver, TNW Jackson, J Lagopoulos… - Progress in Neuro …, 2022 - Elsevier
The so-called “psychedelic renaissance” has stimulated expanded interest in several
classes of drugs that appear to possess transdiagnostic effects in the treatment of mental …

[HTML][HTML] Neuroimaging-derived biomarkers of the antidepressant effects of ketamine

A Zavaliangos-Petropulu, NB Al-Sharif, B Taraku… - Biological psychiatry …, 2023 - Elsevier
Major depressive disorder is a highly prevalent psychiatric disorder. Despite an extensive
range of treatment options, about a third of patients still struggle to respond to available …

Ketamine and the disinhibition hypothesis: neurotrophic factor-mediated treatment of depression

P Borsellino, RI Krider, D Chea, R Grinnell, TA Vida - Pharmaceuticals, 2023 - mdpi.com
Ketamine is a promising alternative to traditional pharmacotherapies for major depressive
disorder, treatment-resistant depression, and other psychiatric conditions that heavily …

Oral ketamine may offer a solution to the ketamine conundrum

M Dutton, AT Can, J Lagopoulos, DF Hermens - Psychopharmacology, 2023 - Springer
Ketamine has received considerable attention for its rapid and robust antidepressant
response over the past decade. Current evidence, in clinical populations, predominantly …

A systematic review of the incidence of medical serious adverse events in sub-anesthetic ketamine treatment of psychiatric disorders

N Hovda, W Gerrish, W Frizzell… - Journal of Affective …, 2024 - Elsevier
Background Limited published data exists that collates serious adverse outcomes involving
ketamine as a psychiatric intervention. This systematic review assesses the reported …