Background Bisphosphonates are specific inhibitors of osteoclastic activity and used in the
treatment of patients with multiple myeloma (MM). While bisphosphonates are shown to be …

Reports of osteonecrosis of the jaw (ONJ) in patients receiving long-term bisphosphonate
therapy have appeared in the literature since 2003. This condition involves avascular …

To identify potential risk factors for the development of osteonecrosis of the jaw (ONJ) in
patients receiving bisphosphonates, we conducted a MEDLINE search. We identified 44 …

Medication-related osteonecrosis of the jaw (MRONJ), a severe side effect caused by
antiresorptive antiangiogenic medication, particularly bisphosphonates (BPs), has become a …

OBJECTIVE: The aim of this study was to histopathologically evaluate the effects of
pamidronate and zoledronate on the mandible in an animal model. STUDY DESIGN: Sixty …

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is an important side effect of
bisphosphonates, whose etiopathogenesis has not been completely elucidated. Theories …

Patients diagnosed with multiple myeloma and metastatic breast, prostate and renal cancers
have a better opportunity for longer survival due to a myriad of chemotherapies regimens …

Purpose To report on a case of osteonecrosis of the jaw (ONJ) in a patient treated with
clodronate, an alkylbiphosphonate, and to draw attention to the risk of ONJ following …

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is mainly observed in patients
with multiple myeloma and bone metastasis from solid tumors receiving iv bisphosphonate …

Osteonecrosis of the Jaw (ONJ) is a recently recognised and potentially highly morbid
complication of bisphosphonate therapy in the setting of metastatic malignancy, including …